当然

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Normal range[edit]

In the Western world, the most typical age range for menopause (last period from natural causes) is between the ages of 40 and 61^[4] and the average age for last period is 51 years.^[5] The average age of natural menopause in Australia is 51.7 years,^[6] although this varies considerably from one woman to another. In India and the Philippines, the median age of natural menopause is considerably earlier, at 44 years.^[7]

Youngest[edit]

In rare cases, a woman's ovaries stop working at a very early age, ranging anywhere from the age of puberty to age 40, and this is known as premature ovarian failure (POF). Spontaneous premature ovarian failure affects 1% of women by age 40, and 0.1% of women by age 30. POF is not considered to be due to the normal effects of aging.

Oldest[edit]

Due to vagaries in records systems throughout the world, an oldest age for which menopause has occurred in a female of the human species is not exactly known. Reports of normal conception and child birth around the age of 70 exist, but are usually subject to controversy. Reports of normal conception beyond age 70 are almost nonexistent. <sup>[8]

百度</sup>

具体表现：

1、30岁左右：皮肤明显出现色斑，松弛、晦暗无光、毛孔粗大、粗糙、痤疮不断等现象；

2、30-40岁之间：出现内分泌紊乱，如月经不调、乳房下垂、外阴干燥、性欲减退等女性性征明显衰退、减弱者以及出现更年期症状的女性；

3、40-55岁之间：出现失眠、多梦、盗汗、潮热、烦躁易怒、精力体力下降、记忆力减退、骨质疏松等更年期症状；

4、55岁以上：肾功能大幅下降，卵巢严重萎缩。