大师之一谢幕,删了。
Study notes:
Before it was possible to examine the immunoglobulin genes directly, there were two main hypotheses for the origin of this diversity. The germline theory held that there is a separate gene for each different immunoglobulin chain and that the antibody repertoire is largely inherited. In contrast, somatic diversification theories proposed that the observed repertoire is generated from a limited number of inherited V-region sequences that undergo alteration within B cells during the individual’s lifetime.
Cloning of the immunoglobulin genes revealed that elements of both theories were correct and that the DNA sequence encoding each V region is generated by rearrangements of a relatively small group of inherited gene segments. Diversity is further enhanced by the process of somatic hypermutation in mature activated B cells. Thus the somatic diversification theory was essentially correct, although the concept of multiple germline genes embodied in the germline theory also proved true.
几位大师经常教导要多读书
所有跟帖:
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赞一个,要的就是这种与日俱进的就是精神,不能吃老本。
-betadine-
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07/11/2014 postreply
08:48:36
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谢谢鼓励。
-26484915-
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07/11/2014 postreply
08:57:04
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impressive! 那就是说你今天认为对的事情,明天可能就会被证明是错的。今天你认为是错的事情,明天可能就会被证明是正确的。
-医者意也-
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07/11/2014 postreply
08:52:41
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科学方法:从假说到理论
-26484915-
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07/11/2014 postreply
09:19:42
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让我告诉你一个事实,科学理论的基础是数学, 连最基本的1+2 = 2+1都是假设。。。
-littlecat8-
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07/11/2014 postreply
09:57:46
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Really???
-26484915-
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07/11/2014 postreply
10:18:08
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请注意这是由另外的假设体系导出交换律, 与此同时, 算术公理体系也可以参考这里 http://en.wikipedia.org/
-littlecat8-
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07/11/2014 postreply
10:41:39
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数学专家,鉴定完毕~~
-随意-
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07/11/2014 postreply
10:44:24
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专家谈不上,只是懂一点皮毛而已。。。
-littlecat8-
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07/11/2014 postreply
10:49:37
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你好像是鉴定专家啊,你上一次那个鉴定我觉得很有水平啊,哈哈
-医者意也-
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07/11/2014 postreply
10:52:55
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thx for noticing my finding on the couple relationship
-随意-
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07/11/2014 postreply
11:43:34
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Can you challenge those?
-26484915-
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07/11/2014 postreply
10:50:29
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公理的意思是我们不能证明是正确,也不能证明它是错的
-littlecat8-
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07/11/2014 postreply
10:58:51
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我忽悠什么呢? 我告诉你吧, 这叫交换公理
-littlecat8-
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07/11/2014 postreply
10:36:00
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科学的假设是很多
-指挥家-
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07/11/2014 postreply
10:51:59
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你说的已经很接近科学的本质,即科学理论不是事实,其本质上还是假设
-littlecat8-
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07/11/2014 postreply
11:08:03
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科学理论当然是最能揭示现实世界的真理的,比如
-指挥家-
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07/11/2014 postreply
11:18:43
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我可以不迷信科学,但我可以应用科学,因为科学是我们创造的工具而已。
-littlecat8-
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07/11/2014 postreply
11:34:44
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这个扯得太远了。比如药品是否有效有毒,与数学公理没有任何关系。
-26484915-
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07/12/2014 postreply
04:32:00
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是否有效是不是基于数字啊?
-littlecat8-
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07/12/2014 postreply
05:24:04
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That's where research comes in.
-26484915-
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07/11/2014 postreply
10:35:22
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To you nobody is as good as you in any area.
-26484915-
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07/11/2014 postreply
12:06:16
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凑合着看吧。
-26484915-
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07/12/2014 postreply
04:14:37
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It looks good to me. Doesn't it look good to you?
-26484915-
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07/12/2014 postreply
05:41:44
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Should be: if you ARE unable ... please write in Chinese.
-26484915-
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07/13/2014 postreply
18:07:43
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对,书多读书再多不会做人也木价值
-随意-
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07/11/2014 postreply
10:49:21
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Like personal attacks online?
-26484915-
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07/11/2014 postreply
10:51:07
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if not agree state your thoughts without attacking~~
-随意-
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07/11/2014 postreply
10:53:57
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Agreed!
-26484915-
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07/11/2014 postreply
13:08:38
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赞!也请写点自己的东西出来给网友学习科普,中文最好,期盼呀。。。.
-ME_Professor-
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07/11/2014 postreply
10:46:56
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我自己也在写论文:用海洋能源发电,可惜,放到健坛不合适。以后开老人农场,能源问题找我。呵呵。
-ME_Professor-
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07/11/2014 postreply
10:59:20
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What a Hot and Sexy Topic~~
-随意-
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07/11/2014 postreply
11:06:47
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thanks.
-ME_Professor-
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07/11/2014 postreply
11:16:23
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哇,有兴趣。好。show-off 一下。原理如下:
-ME_Professor-
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07/11/2014 postreply
12:11:13
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早就有了
-houtou72-
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07/11/2014 postreply
14:05:41
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您说的对!有不同的设计版本,关键是成本高,如何提高效率和减低成本,还是要挖掘很久。
-ME_Professor-
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07/11/2014 postreply
14:58:35
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以后开老人农场,能源问题找我- I buy the land, you provide the energy?
-tantema-
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07/11/2014 postreply
12:37:31
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君子一言!
-ME_Professor-
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07/11/2014 postreply
15:13:16
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请2648兄写点免疫的东西,我很想学习, 如:增加免疫力真相。
-ME_Professor-
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07/11/2014 postreply
11:23:07
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增加免疫力真相
-26484915-
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07/11/2014 postreply
11:25:38
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请晒晒读过的中医书,期待~~
-随意-
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07/11/2014 postreply
11:09:28
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You first~~~
-26484915-
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07/11/2014 postreply
11:11:14
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支持晒,偶们有眼福了~
-随意-
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07/11/2014 postreply
12:00:24
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知道你想要说明什么,但你的笔记说明你似乎仍然没有能切入到最关键的问题上。
-houtou72-
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07/11/2014 postreply
14:02:49
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What is the key in your opinion
-26484915-
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07/11/2014 postreply
14:35:13