美国科学家在著名杂志Nature Medicine 发研究文称COVID-19 既不是人工合成的也不是实验室养的野生的在

来源: xsz 2020-04-15 21:59:58 [] [旧帖] [给我悄悄话] 本文已被阅读: 0 次 (10138 bytes)

培养传代过程中导致的突变种。作者在ABC News访问中还认为武汉海鲜市场不是源头,还认为可能低毒性的病毒早在人类中传播数年甚至几十年了,发生突变后形成了这个高毒高传染性的病毒。美国国立卫生研究院的头认同这文章COVIN-19非人工制造的结论。

可以让你女儿看一下下面的文章

https://www.nature.com/articles/s41591-020-0820-9

The proximal origin of SARS-CoV-2

Our analyses clearly show that SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus” “In theory, it is possible that SARS-CoV-2 acquired RBD mutations (Fig. 1a) during adaptation to passage in cell culture..........Subsequent generation of a polybasic cleavage site would have then required repeated passage in cell culture or animals with ACE2 receptors similar to those of humans, but such work has also not previously been described. Finally, the generation of the predicted O-linked glycans is also unlikely to have occurred due to cell-culture passage, as such features suggest the involvement of an immune system”

该文作者对ABC News 说他认为武汉海鲜市场不是源头应有更早的源头。还认为可能表面蛋白的突变导致该病在人类的爆发也可能该病毒的低毒版本早已在人身上传播了数年几十年了突变后形成了这个高毒性高传染性的病毒

https://abcnews.go.com/US/conspiracy-theorists-study-concludes-covid-19-laboratory-construct/story?id=69827832

“The mutation in surface proteins, according to Garry, could have triggered the outbreak of the pandemic, but it’s also possible that a less severe version of the illness was circulating through the population for years, perhaps even decades, before escalating to this point.”

“And while many believe the virus originated at a fish market in Wuhan, China, Garry said that is also a misconception.”

"Our analyses, and others too, point to an earlier origin than that," Garry said. "There were definitely cases there, but that wasn’t the origin of the virus."

NIH Director 支持该文COVID-19 非人工制造的结论

https://directorsblog.nih.gov/2020/03/26/genomic-research-points-to-natural-origin-of-covid-19/

Genomic Study Points to Natural Origin of COVID-19

So, what is the natural origin of the novel coronavirus responsible for the COVID-19 pandemic? The researchers don’t yet have a precise answer. But they do offer two possible scenarios.

In the first scenario, as the new coronavirus evolved in its natural hosts, possibly bats or pangolins, its spike proteins mutated to bind to molecules similar in structure to the human ACE2 protein, thereby enabling it to infect human cells. This scenario seems to fit other recent outbreaks of coronavirus-caused disease in humans, such as SARS, which arose from cat-like civets; and Middle East respiratory syndrome (MERS), which arose from camels.

The second scenario is that the new coronavirus crossed from animals into humans before it became capable of causing human disease. Then, as a result of gradual evolutionary changes over years or perhaps decades, the virus eventually gained the ability to spread from human-to-human and cause serious, often life-threatening disease.

Either way, this study leaves little room to refute a natural origin for COVID-19. And that’s a good thing because it helps us keep focused on what really matters: observing good hygiene, practicing social distancing, and supporting the efforts of all the dedicated health-care professionals and researchers who are working so hard to address this major public health challenge.

Finally, next time you come across something about COVID-19 online that disturbs or puzzles you, I suggest going to FEMA’s new Coronavirus Rumor Control web site. It may not have all the answers to your questions, but it’s definitely a step in the right direction in helping to distinguish rumors from facts.”

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