楼上的论文连接: Cryptic adaptation to humans, a specific insertion or r

a specific insertion or recombination event is required to enable the emergence of SARS-CoV-2 as an epidemic pathogen.

 It is also questionable whether generation of the O-linked glycans would have occurred on cell culture passage, as such mutations typically suggest the involvement of an immune system, that is not present  in vitro .

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