A Muscle-Centric Perspective on Intermittent Fasting - 油管上看的

油管上看到有人提这个文章，我搜了一下，他们觉得 intermittent fasting likely represents a suboptimal dietary approach to remodel skeletal muscle, which could impact the ability to maintain or enhance muscle mass and quality, especially during periods of reduced energy availability.

 https://pubmed.ncbi.nlm.nih.gov/34179054/

Muscle protein is constantly "turning over" through the breakdown of old/damaged proteins and the resynthesis of new functional proteins, the algebraic difference determining net muscle gain, maintenance, or loss. This turnover, which is sensitive to the nutritional environment, ultimately determines the mass, quality, and health of skeletal muscle over time. Intermittent fasting has become a topic of interest in the health community as an avenue to improve health and body composition primarily via caloric deficiency as well as enhanced lipolysis and fat oxidation secondary to attenuated daily insulin response. However, this approach belies the established anti-catabolic effect of insulin on skeletal muscle. More importantly, muscle protein synthesis, which is the primary regulated turnover variable in healthy humans, is stimulated by the consumption of dietary amino acids, a process that is saturated at a moderate protein intake. While limited research has explored the effect of intermittent fasting on muscle-related outcomes, we propose that infrequent meal feeding and periods of prolonged fasting characteristic of models of intermittent fasting may be counter-productive to optimizing muscle protein turnover and net muscle protein balance. The present commentary will discuss the regulation of muscle protein turnover across fasted and fed cycles and contrast it with studies exploring how dietary manipulation alters the partitioning of fat and lean body mass. It is our position that intermittent fasting likely represents a suboptimal dietary approach to remodel skeletal muscle, which could impact the ability to maintain or enhance muscle mass and quality, especially during periods of reduced energy availability.

 

所有跟帖： 

• 这个，我觉得GG和旺旺更有说服力。他们是很典型的IF但是一身是肌肉和力量。网络各种说法都有。 -古来万事- ♀ (0 bytes) () 10/19/2022 postreply 06:25:17

• 我直觉也是觉得IF对肌肉不友好。我玩命吃了一个月比较健康的饮食也没增重就放弃了。IF岂不更瘦了？我对IF比较感兴趣是延缓 -让理想飞- ♀ (54 bytes) () 10/19/2022 postreply 08:00:16

• 我觉得有认真锻炼的习惯和健康饮食的意识，接下来就是几十年的坚持和不断进步，虽然可能比较慢。我最佩服L94607 -fitness2022- ♀ (298 bytes) () 10/19/2022 postreply 08:37:34

• 我是相信习惯成自然。不论是养成好习惯还是改掉不良习惯都是这样。 -古来万事- ♀ (0 bytes) () 10/19/2022 postreply 09:00:05

• 感觉做这种间歇饥饿的，绝大多数都是比较有健康意识的，饮食其他方面应该也很注意 -羽绒服- ♂ (0 bytes) () 10/19/2022 postreply 10:12:51

• 终于有时间找来了这篇文献的原文。 作者是多伦多大学教PE的，写的蛮有意思的，不过他们都是理论推测 -GoGym- ♀ (434 bytes) () 10/19/2022 postreply 10:15:42

• 赞认真。我就只看了abstract -fitness2022- ♀ (0 bytes) () 10/19/2022 postreply 21:37:15