御姐好，她们放疗好像会导致更多肿瘤，我上面写的令人糊涂了，改一下。。。

来源: 志在千里 于 2015-11-14 21:38:25 [] [旧帖] [给我悄悄话] 阅读数 : (947 bytes)
本帖于 2015-11-14 21:49:16 时间, 由普通用户 志在千里 编辑
回答: ATM基因者的放疗效果不佳。。。。 由 御用文人 于 2015-11-14 21:32:39

御姐好，因为对DNA突变后的修复有问题，她们放疗好像会导致更多肿瘤，我上面写的令人糊涂了，改一下。。。

https://en.wikipedia.org/wiki/Ataxia_telangiectasia

Cancer and radiosensitivity

In the absence of the ATM protein, cell-cycle check-point regulation and programmed cell death in response to DSBs are defective. The result is genomic instability which can lead to the development of cancers.[25]

Irradiation and radiomimetic compounds induce DSBs which are unable to be repaired appropriately when ATM is absent. Consequently, such agents can prove especially cytotoxic to A-T cells and people with A-T.

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