御姐好,她们放疗好像会导致更多肿瘤,我上面写的令人糊涂了,改一下。。。

来源: 2015-11-14 21:38:25 [旧帖] [给我悄悄话] 本文已被阅读:

御姐好,因为对DNA突变后的修复有问题,她们放疗好像会导致更多肿瘤,我上面写的令人糊涂了,改一下。。。

https://en.wikipedia.org/wiki/Ataxia_telangiectasia

Cancer and radiosensitivity

In the absence of the ATM protein, cell-cycle check-point regulation and programmed cell death in response to DSBs are defective. The result is genomic instability which can lead to the development of cancers.[25]

Irradiation and radiomimetic compounds induce DSBs which are unable to be repaired appropriately when ATM is absent. Consequently, such agents can prove especially cytotoxic to A-T cells and people with A-T.