方法是病史,体检,PCR和dot-blot hybridization methods。 基本上要有分子生物学和流行病学的基础知识的。 这篇文章有900多个citation呢。
以下这篇文章认为处女和非处女HPV检出率没有显著区别。用的也是PCR。 这是在台湾做的。
Possible non-sexual transmission of genital human papillomavirus infections in young women.
Pao CC , Tsai PL , Chang YL , Hsieh TT , Jin JY
Eur J Clin Microbiol Infect Dis.1993 Mar ; 12(3):221-2.
Human papillomaviruses were detected by an in vitro enzymatic DNA amplification method in cells obtained from vulvar swabs of 9 of 61 (14.8%) young women without prior experience of sexual intercourse and in 7 of 57 (12.3%) young women with prior experience. The prevalence of human papillomavirus DNA in these two groups of women was not significantly different (x2 = 0.16, p > 0.5; 95% confidence interval -0.165 to 0.215). These results suggest that genital human papillomavirus is not sexually transmitted in all cases and that it may be acquired by modes other than sexual contact.
PMID: 8389707 [PubMed - indexed for MEDLINE]
方法是病史,体检,PCR和dot-blot hybridization methods
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wow! this conclusion is so strong!
-liushui2007-
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11/05/2014 postreply
19:38:28