方法是病史,体检,PCR和dot-blot hybridization methods

来源: 2014-11-05 19:19:05 [旧帖] [给我悄悄话] 本文已被阅读:

方法是病史,体检,PCR和dot-blot hybridization methods。 基本上要有分子生物学和流行病学的基础知识的。 这篇文章有900多个citation呢。
以下这篇文章认为处女和非处女HPV检出率没有显著区别。用的也是PCR。 这是在台湾做的。

Possible non-sexual transmission of genital human papillomavirus infections in young women.
Pao CC , Tsai PL , Chang YL , Hsieh TT , Jin JY
Eur J Clin Microbiol Infect Dis.1993 Mar ; 12(3):221-2.

Human papillomaviruses were detected by an in vitro enzymatic DNA amplification method in cells obtained from vulvar swabs of 9 of 61 (14.8%) young women without prior experience of sexual intercourse and in 7 of 57 (12.3%) young women with prior experience. The prevalence of human papillomavirus DNA in these two groups of women was not significantly different (x2 = 0.16, p > 0.5; 95% confidence interval -0.165 to 0.215). These results suggest that genital human papillomavirus is not sexually transmitted in all cases and that it may be acquired by modes other than sexual contact.
PMID: 8389707 [PubMed - indexed for MEDLINE]