This is how she described the process

Inflamed epithelium provides adhesion molecules to trap and hold macrophages

Macrophages through scavenger process take up oxidized LDL and become foam cells

Interleukins and growth factors promote proliferation of smooth muscle cells (artery thickening)

Extracellular matrix proteins are degraded

Vulnerable plaque eruption : thrombosis


It does not ignore the role oxidized LDL-p plays in the process.
This theory treats the inflammation of the epithelium as the very first step.
However, there is another theory which depicts the oxidation of LDL-p as the initial and a key step. And what causes the oxidation of LDL-p? LDL receptor's clearance of LDL-p plays a role as well.

So she has an interesting theory but it is not the whole picture.

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Her whole picture, -益生菌- 给 益生菌 发送悄悄话 益生菌 的博客首页 (1303 bytes) () 12/01/2014 postreply 21:16:33

读了好几遍,有不少疑点。待消化一些后再问问题。可能问题会很多!谢谢 -Lily168- 给 Lily168 发送悄悄话 Lily168 的博客首页 (0 bytes) () 12/01/2014 postreply 22:18:34

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