要点:
疫情期间,成人每天应该服用VD 4000 IU, 至少2000,要保证25(OH)D serum levels over 30ng/ml (75nmol/L)
An Open Letter Urges Government's Worldwide to Use Vitamin D as Part of COVID Response Strategy
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An open letter signed by 138 global experts has been distributed to government's around the world, urging them to make vitamin D part of their coronavirus response strategy after much evidence has suggested the vitamin may reduce transmission, hospitalisation and even death rates.
Previous research has already suggested that those who are hospitalized with COVID-19 may experience less severe complications if their levels of vitamin D is sufficiently high. However, despite the research, the UK’s National Institute for Health and Care Excellence (Nice) has recently concluded that ‘there is currently not enough evidence to support taking vitamin D solely to prevent or treat COVID-19’.
The letter was sent to Boris Johnson and health Secretary Mike Hancock on Monday the 21st of December, advising that healthy adults should increase their daily vitamin D intake to 2,000 - 4000 international units (IU) during the pandemic.
PS
The open letter
https://vitamindforall.org/letter.html
Therefore, we call on all governments, doctors, and healthcare workers worldwide to immediately recommend and implement efforts appropriate to their adult populations to increase vitamin D, at least until the end of the pandemic. Specifically to:
- Recommend amounts from all sources sufficient to achieve 25(OH)D serum levels over 30ng/ml (75nmol/L), a widely endorsed minimum with evidence of reduced COVID-19 risk.
- Recommend to adults vitamin D intake of 4000 IU (100mcg) daily (or at least 2000 IU) in the absence of testing. 4000 IU is widely regarded as safe.5
- Recommend that adults at increased risk of deficiency due to excess weight, dark skin, or living in care homes may need higher intakes (eg, 2x). Testing can help to avoid levels too low or high.
- Recommend that adults not already receiving the above amounts get 10,000 IU (250mcg) daily for 2-3 weeks (or until achieving 30ng/ml if testing), followed by the daily amount above. This practice is widely regarded as safe. The body can synthesize more than this from sunlight under the right conditions (e.g., a summer day at the beach). Also, the NAM (US) and EFSA (Europe) both label this a “No Observed Adverse Effect Level” even as a daily maintenance intake.
- Measure 25(OH)D levels of all hospitalized COVID-19 patients & treat w/ calcifediol or D3, to at least remedy insufficiency <30ng/ml (75nmol/L), possibly with a protocol along the lines of Castillo et al ‘20 or Rastogi et al '20, until evidence supports a better protocol.