孩子有自闭症的问题,40岁以上产妇,与25-29年龄段产妇相比,风险增加51%;与25岁以下产妇相比,风险增加77%。据此换算,如果40岁以上产妇孩子有自闭症的风险为100,那么:
产妇年龄段 相对风险
<25 56.5
25-29 66.2
>40 100
另外,有文献指出,高龄产妇生下的女孩,偏男性化。
信息来源:
Study Confirms Link between Older Maternal Age and Autism,Maternal age and autism are both on the rise--but only a small fraction of the increasing incidence can be explained by the trend toward later childbearing
https://www.scientificamerican.com/article/autism-maternal-age/
The researchers found that mothers over 40 had a 51 percent higher risk of having a child with autism than mothers 25 to 29, and a 77 percent higher risk than mothers under 25. Autism—a developmental disorder characterized by impaired social interaction and communication—appears to be on the rise.