剂量有点大：300 mg/kg for a week in mice,原文见内

如果按此剂量，七十五公斤成人，要用22.5克甘草苷。

这东东在甘草中的含量约为0.2%，每天要吃十一公斤甘草，才能达到这个量。

吃货兄，看你的肚量了。

 

https://www.biorxiv.org/content/10.1101/2020.05.02.074021v1

 

We found liquiritin significantly inhibit replication of SARS-CoV-2 in Vero E6 cells with EC50 = 2.39 μM. Mechanistically, we found liquiritin exerts anti-viral function by mimicking type I interferon. Upregulated genes induced by liquiritin are enriched in GO categories including type I interferon signaling pathway, negative regulation of viral genome replication and etc. In toxicity experiment, no death was observed when treated at dose of 300 mg/kg for a week in ICR mice. All the organ indexes but liver and serum biochemical indexes were normal after treatment. Liquiritin is abundant in licorice tablet (~0.2% by mass), a traditional Chinese medicine. Together, we recommend liquiritin as a competitive candidate for treating COVID-19.