FDA今年十月刚批准的疗法(CAR T-cell therapy),但是有条件限制。烦请各位好人帮忙看一下。

这样,我好对照朋友情况看看她是否适合接受这种治疗。

 

Conditions treated

The FDA-approved indications for CAR T-cell therapy, Yescarta made by Kite Pharma Gilead, is aggressive B-cell non-Hodgkin's lymphoma, including the diagnosis of:

  • Diffuse large B-cell lymphoma
  • Primary mediastinal B-cell lymphoma
  • Large B-cell lymphoma transformed from follicular lymphoma
  • Aggressive B-cell lymphoma not otherwise specified (NOS)

Patients who have relapsed or refractory disease after two or more types of prior treatments could be evaluated for CAR T-cell therapy with Yescarta.

In addition, Mayo Clinic has multiple active clinical trials testing CAR T-cell therapy in lymphoma and other cancer types.

 

请问:

“including the diagnosis of:

  • Diffuse large B-cell lymphoma
  • Primary mediastinal B-cell lymphoma
  • Large B-cell lymphoma transformed from follicular lymphoma
  • Aggressive B-cell lymphoma not otherwise specified (NOS)”

这段话是什么意思啊?是这种疗法要做的事?这种疗法需要的前提?还是这种疗法需要确诊上述问题?

拜谢!

 

 

所有跟帖: 

你朋友是得了淋巴癌?按类型看对不的上就是 -yddad- 给 yddad 发送悄悄话 (0 bytes) () 11/16/2017 postreply 09:20:49

不是淋巴,是胰腺。 -stonebench- 给 stonebench 发送悄悄话 stonebench 的博客首页 (0 bytes) () 11/16/2017 postreply 09:28:01

批准的疗法现在只是对一些类型的淋巴癌 -yddad- 给 yddad 发送悄悄话 (0 bytes) () 11/16/2017 postreply 09:38:38

谢谢! -stonebench- 给 stonebench 发送悄悄话 stonebench 的博客首页 (0 bytes) () 11/16/2017 postreply 09:45:08

这是适应症,有这以上情况的可以用。 -锅沿- 给 锅沿 发送悄悄话 (0 bytes) () 11/16/2017 postreply 09:35:26

谢谢! -stonebench- 给 stonebench 发送悄悄话 stonebench 的博客首页 (0 bytes) () 11/16/2017 postreply 09:45:34

最后一行,尤其最后三字:Mayo Clinic现有几个进行中的临试,使用这种疗法针对淋巴瘤和其他癌。 -fuz- 给 fuz 发送悄悄话 fuz 的博客首页 (59 bytes) () 11/16/2017 postreply 09:49:53

大谢!!! -stonebench- 给 stonebench 发送悄悄话 stonebench 的博客首页 (0 bytes) () 11/16/2017 postreply 09:54:51

clinical trial here -致青春- 给 致青春 发送悄悄话 致青春 的博客首页 (437 bytes) () 11/16/2017 postreply 10:16:34

打不开,请再发一次。谢谢! -stonebench- 给 stonebench 发送悄悄话 stonebench 的博客首页 (0 bytes) () 11/16/2017 postreply 10:30:26

找到现在的两个对 胰腺癌的 CAR-T trials -yddad- 给 yddad 发送悄悄话 (784 bytes) () 11/16/2017 postreply 10:34:21

多谢啦! -stonebench- 给 stonebench 发送悄悄话 stonebench 的博客首页 (0 bytes) () 11/16/2017 postreply 10:58:15

刚打了电话,主要是针对淋巴瘤的。 -stonebench- 给 stonebench 发送悄悄话 stonebench 的博客首页 (0 bytes) () 11/16/2017 postreply 10:31:13

现在的CART 个体化治疗 -致青春- 给 致青春 发送悄悄话 致青春 的博客首页 (204 bytes) () 11/16/2017 postreply 10:45:00

刚才匆匆忙忙写错了一点 ,刚刚纠正 -致青春- 给 致青春 发送悄悄话 致青春 的博客首页 (0 bytes) () 11/16/2017 postreply 10:47:59

告诉你朋友,钱不是万能的 -白兔妈- 给 白兔妈 发送悄悄话 白兔妈 的博客首页 (76 bytes) () 11/16/2017 postreply 11:34:13

It's for B-cell only. The most they used were B-cell ALL so far. -houmaoyisheng- 给 houmaoyisheng 发送悄悄话 (0 bytes) () 11/16/2017 postreply 12:46:33

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