N年以前，我的甘油三酯高达500，后来不知什么原因逐渐减下来，但还是较高。

来源: 吃与活 于 2016-06-05 06:35:39 [] [博客] [旧帖] [给我悄悄话] 阅读数 : (5209 bytes)
回答: Triglycerides高有啥不好和危险？ 由 Gbdjw 于 2016-06-04 16:40:50

周福满饮食后，有所下降，去年达到100以内。

我觉得甘油三酯与碳水化合物（米饭馒头等）摄入量有关，吃富含omega-3的鱼可能会使之下降。鱼油也会起作用。

高的坏处是什么？ 高的甘油三酯与冠心病，中风（缺血性）相关，也可能导致胰岛素分泌降低，引起糖尿病。

甘油三酯引起心血管疾病的可能原理：它是残余胆固醇（remnant cholesterol） 脂蛋白的重要成分，它可进入血管内膜，由于体积大，不容易出来。甘油三酯可以被代谢掉，但胆固醇不能。甘油三酯的代谢产物可能会引起局部炎症。胆固醇进入巨噬细胞，导致泡沫细胞的形成，进而形成硬化斑。见下图，来自

2014 Aug 16;384(9943):626-35. doi: 10.1016/S0140-6736(14)61177-6.

Triglycerides and cardiovascular disease.

Nordestgaard BG1, Varbo A2.

Abstract

After the introduction of statins, clinical emphasis first focussed on LDL cholesterol-lowering, then on the potential for raising HDL cholesterol, with less focus on lowering triglycerides. However, the understanding from genetic studies and negative results from randomised trials that low HDL cholesterol might not cause cardiovascular disease as originally thought has now generated renewed interest in raised concentrations of triglycerides. This renewed interest has also been driven by epidemiological and genetic evidence supporting raised triglycerides, remnant cholesterol, or triglyceride-rich lipoproteins as an additional cause of cardiovascular disease and all-cause mortality. Triglycerides can be measured in the non-fasting or fasting states, with concentrations of 2-10 mmol/L conferring increased risk of cardiovascular disease, and concentrations greater than 10 mmol/L conferring increased risk of acute pancreatitis and possibly cardiovascular disease. Although randomised trials showing cardiovascular benefit of triglyceride reduction are scarce, new triglyceride-lowering drugs are being developed, and large-scale trials have been initiated that will hopefully provide conclusive evidence as to whether lowering triglycerides reduces the risk of cardiovascular disease.

Copyright © 2014 Elsevier Ltd. All rights reserved.

PMID:
25131982
[PubMed - indexed for MEDLINE]
 
 

 

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