'60 Minutes': FDA fast tracks cancer treatment using polio virus
The Food and Drug Administration has given an experimental cancer treatment breakthrough status, as CBS' "60 minutes" reported Sunday. Tests at Duke University have been so successful that the FDA will make the treatment available to hundreds of patients while it’s still being evaluated for final approval. The treatment uses the polio virus to attack an aggressive form of brain cancer called glioblastoma. Duke neuro-oncologist Dr. Henry Friedman told “60 Minutes” the polio treatment is “the most promising therapy I’ve seen in my career, period.” The polio virus seeks out and attaches to a receptor on the surface of the cells that commonly make up solid tumors. The team at Duke re-engineered ...'60 Minutes': FDA fast tracks cancer treatment using polio virus
The Food and Drug Administration has given an experimental cancer treatment breakthrough status, as CBS' "60 minutes" reported Sunday.
The treatment uses the polio virus to attack an aggressive form of brain cancer called glioblastoma.
Duke neuro-oncologist Dr. Henry Friedman told “60 Minutes” the polio treatment is “the most promising therapy I’ve seen in my career, period.”
The polio virus seeks out and attaches to a receptor on the surface of the cells that commonly make up solid tumors. The team at Duke re-engineered the virus so that it cannot reproduce in normal cells and cause paralysis or death as the normal polio virus does.
The immune system, which typically is unable to attack cancer cells, recognizes the polio virus and can begin to attack brain tumors on its own.
The FDA’s decision to grant “breakthrough status” to the method will allow the experiments to expand to about 40 institutions and hundreds of patients. If that goes well, Duke will be able to skip the third phase of clinical trials and begin to make the treatment available to the public.
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