这个样子,可能目前不适合任何抗肿瘤治疗。

来源: Diana-Sun 2016-05-13 17:56:31 [] [博客] [旧帖] [给我悄悄话] 本文已被阅读: 次 (16508 bytes)

病人目前的一般情况按ECOG打分为3-4分。具体见下表。

抗肿瘤治疗一般在患者ECOG 0-1 时进行。有时可以放宽到2。

可以用中药支持治疗,中西医结合会更好。有贫血的要输血,有粒细胞减少/缺乏的要用集落刺激因子,有水、电解质、酸碱失衡的要纠正,有抑郁的要抗抑郁治疗帮助恢复体力,有感染的要抗感染治疗等等。

等一般情况好转了,再考虑抗肿瘤治疗。这里是Drugs Approved for Non-Hodgkin Lymphoma。 应先考虑使用这些药物/方案,毕竟是临床试验证明有效的。pembrolizumab在血液肿瘤的疗效还不确定,在实体瘤也不是每种类型效果都好的。

Karnofsky Status Karnofsky Grade ECOG Grade ECOG Status
Normal, no complaints 100 0 Fully active, able to carry on all pre-disease performance without restriction
Able to carry on normal activities. Minor signs or symptoms of disease 90 1 Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work
Normal activity with effort 80 1 Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work
Care for self. Unable to carry on normal activity or to do active work 70 2 Ambulatory and capable of all selfcare but unable to carry out any work activities. Up and about more than 50% of waking hours
Requires occasional assistance, but able to care for most of his needs 60 2 Ambulatory and capable of all selfcare but unable to carry out any work activities. Up and about more than 50% of waking hours
Requires considerable assistance and frequent medical care 50 3 Capable of only limited selfcare, confined to bed or chair more than 50% of waking hours
Disabled. Requires special care and assistance 40 3 Capable of only limited selfcare, confined to bed or chair more than 50% of waking hours
Severly disabled. Hospitalisation indicated though death nonimminent 30 4 Completely disabled. Cannot carry on any selfcare. Totally confined to bed or chair
Very sick. Hospitalisation necessary. Active supportive treatment necessary 20 4 Completely disabled. Cannot carry on any selfcare. Totally confined to bed or chair
Moribund 10 4 Completely disabled. Cannot carry on any selfcare. Totally confined to bed or chair
Dead 0 5 Dead

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非常感谢您的回复和信息,会和家人一起讨论。谢谢! -Ghost99- 给 Ghost99 发送悄悄话 Ghost99 的博客首页 (0 bytes) () 05/14/2016 postreply 06:22:46

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