Myasthenia gravis（MG） is a chronic autoimmune neuromuscular disorder that is characterized by fluctuating weakness of the voluntary muscle groups. In the most common cases, muscle weakness is caused by circulating antibodies that block acetylcholine receptors at the postsynaptic neuromuscular junction, inhibiting the excitatory effects of the neurotransmitter acetylcholine on nicotinic receptors at neuromuscular junctions.
Myasthenia gravis is treated with medications such as acetylcholinesterase inhibitors or immunosuppressants, and, in selected cases, thymectomy (surgical removal of the thymus gland).
ALS, , the term is commonly used as motor neurone disease In the United Kingdom.
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
重症肌无力（Myasthenia Gravis）并非神经退化，而是神经肌肉接头的突触后膜的乙酰胆碱受体被阻断。该病可用乙酰胆碱酯酶抑制剂或免疫抑制剂药来治疗。
肌萎缩性侧索硬化（Amyotrophic lateral sclerosis ）导致运动神经元退化，目前无药可治。
多发性硬化症（Multiple Sclerosis）导致神经鞘退化，目前无药可治，但有要可延缓。
后两者与神经退化病变有关。寒枝的病人，神经萎缩型肌无力应属于肌萎缩性侧索硬化。
