several slow-releasing H(2)S prodrugs are currently under develo

Antioxid Redox Signal. 2012 Jul 1;17(1):119-40. doi: 10.1089/ars.2012.4612. Epub 2012 Apr 20.
Hydrogen sulfide in biochemistry and medicine.
Predmore BL1, Lefer DJ, Gojon G.
Author information

1Department of Surgery-Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
SIGNIFICANCE:

An abundance of experimental evidence suggests that hydrogen sulfide (H(2)S) plays a prominent role in physiology and pathophysiology. Many targets exist for H(2)S therapy. The molecular targets of H(2)S include proteins, enzymes, transcription factors, and membrane ion channels.
RECENT ADVANCES:

Novel H(2)S precursors are being synthesized and discovered that are capable of releasing H(2)S in a slow and sustained manner. This presents a novel and advantageous approach to H(2)S therapy for treatment of chronic conditions associated with a decline in endogenous H(2)S, such as diabetes and cardiovascular disease.

所有跟帖： 

• 缓慢的释放硫化氢进入效应器可产生正面的作用，有利于糖尿病和心血管病。谢谢这个有用的信息。 -御用文人- ♀ (0 bytes) () 07/19/2015 postreply 23:27:05

• 谢谢分享，很有用的信息。很有力的佐证。再次说明量的概念非常非常重要。 -欲千北- ♂ (0 bytes) () 07/20/2015 postreply 09:58:32