我记得 Fosamax 有引起下颌骨坏死的案例，下面是 FDA 对于使用这两种药物的相似处和警告

Fosamax 是传统的抗骨质酥松药物。而 Zometa 主要是抗骨转移癌引起的骨质酥松药物。二者都有一些危险性。。

FDA Warning: Fosamax, Aredia, Zometa

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3/19/2010 NEWS: Patients and healthcare professionals may have questions about oral bisphosphonate medications and atypical subtrochanteric femur fractures, fractures in the bone just below the hip joint. Oral bisphosphonates are commonly prescribed to prevent or treat osteoporosis in postmenopausal women. Common brand names of medications in this class include Fosamax, Actonel, Boniva, and Reclast.

The Food and Drug Administration monitors the potential side effects of popular drugs in order to ensure public health and safety.  Drugs such as Fosamax, Aredia, and Zometa have been the objects of such recent speculation about their risks vs. benefits, due to a rising number of claims that these drugs can be responsible for several serious side effects.

The FDA Alerts: Fosamax, Aredia, and Zometa began with a letter dated September 24, 2004 that was sent to oncologists, dentists, and other healthcare professionals to inform them about the propensity of Novartis' Zometa to cause severe dental side effects.  This letter was followed by another warning to dentists and doctors in May 2005 about the risks of Aredia, Novartis' other bisphosphonate drug.

In August, 2004, Fosamax was a target of an FDA Office of Drug Safety Postmarketing Safety Review panel recommendation that packaging for bisphosphonate drugs like Fosamax such as Zometa, Aredia, and Actone immediately carry stern warnings about the potential for serious complications such as osteonecrosis of the jaw.  Recent class action lawsuits contend that it took Merck almost a year to alter the packaging for Fosamax to warn people of the increased danger. 

Doctors wrote 22.4 million prescriptions for Fosamax in 2005, and each one of these people could potentially suffer the misery of a broken femur bone.  If you or someone you know developed this devastating condition or another Fosamax side effect, you need to consult with a compassionate and experienced attorney immediately.  You may be able to take legal action against those responsible for your agonizing condition, and you could be entitled to a financial compensation package for your physical pain and emotional suffering. 

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• 回复：我记得 Fosamax 有引起下颌骨坏死的案例，下面是 FDA 对于使用这两种药物的相似处和警告 -fruitvale- ♂ (21 bytes) () 05/14/2012 postreply 15:40:12