关于避孕药,百分之十二是怎么算出来的?

来源: dudaan 2010-03-14 05:50:52 [] [博客] [旧帖] [给我悄悄话] 本文已被阅读: 次 (1682 bytes)
伦敦的免费小报Metro用了耸人听闻的手法来报道最近的那项关于避孕药的研究,我觉得这很容易误导。
找到一篇比较平实的报道:
Slightly higher rates were found among younger women who had used oral contraception, with 20 more deaths per 100,000 among those younger than 30, and four more deaths per 100,000 among 30-39 year olds.

But by the age of 50, the benefits outweighed these modest risks, with 14 fewer deaths per 100,000 among 40-49 year olds; 86 fewer deaths per 100,000 for 50-59 year olds; 122 fewer deaths per 100,000 for 60-69 year olds; and 308 fewer deaths per 100,000 for 70+ year olds.

Hannaford says: "Many women, especially those who used the first generation of oral contraceptives many years ago, are likely to be reassured by our results. However, our findings might not reflect the experience of women using oral contraceptives today, if currently available preparations have a different risk than earlier products."

The authors conclude that their results, derived from a relatively healthy UK study group, show that "oral contraception is not significantly associated with an increased long-term risk of death … indeed a net benefit was apparent." However, they point out that "the balance of risks and benefits may vary globally, depending upon patterns of oral contraception usage and background risk of disease."

我觉得这里面还是缺乏重要数据。十万人里多死亡二十人好像是很小的数字,但要注意,30岁以前的死亡率是很低的。而七十岁以上死亡率很高,308人也就不是多太多。不说出具体数字很难让我信服。

最后几句话更重要。

还有,84-86年联合国的权威性研究主要是把避孕药和乳腺癌联系起来,并且也是指出对年轻女性风险更大。

所有跟帖: 

对不起,是82-84年,这次的研究没有说乳腺癌 -dudaan- 给 dudaan 发送悄悄话 dudaan 的博客首页 (654 bytes) () 03/14/2010 postreply 05:54:44

80年代初好像还没有新型复合避孕药呢。不妨看看96年的研究 -flywhc- 给 flywhc 发送悄悄话 flywhc 的博客首页 (914 bytes) () 03/15/2010 postreply 04:34:42

很有道理,统计得出的结论可能很有欺骗性,数据 -出入自在- 给 出入自在 发送悄悄话 出入自在 的博客首页 (321 bytes) () 03/14/2010 postreply 12:26:43

同意. 我当时看了就觉得有疑问. -小谋- 给 小谋 发送悄悄话 小谋 的博客首页 (0 bytes) () 03/14/2010 postreply 13:39:20

西医惯常用相对比率来放大自己的疗效。比如说,乳房筛检每3000人才能救一个人的事实就很少为人所知 -医者意也- 给 医者意也 发送悄悄话 医者意也 的博客首页 (0 bytes) () 03/15/2010 postreply 08:29:49

严谨的科学事实容易引起世人怀疑,传统观念难改啊。这不是简单统计结果 -flywhc- 给 flywhc 发送悄悄话 flywhc 的博客首页 (1295 bytes) () 03/15/2010 postreply 04:24:34

此外,避孕药并不引起体重增加,也不影响生育。详见维基百科 -flywhc- 给 flywhc 发送悄悄话 flywhc 的博客首页 (166 bytes) () 03/15/2010 postreply 04:37:53

不用说这么多,只要把各年龄组死亡人数对比公布即可 -dudaan- 给 dudaan 发送悄悄话 dudaan 的博客首页 (71 bytes) () 03/15/2010 postreply 07:01:32

引用的数据很多,不用抓住一个12诡辩 -flywhc- 给 flywhc 发送悄悄话 flywhc 的博客首页 (252 bytes) () 03/15/2010 postreply 07:53:07

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