"feed" has two layers of meaning here
1) calorie feed: sugar, whole wheat bread, tofu, butter or even patient's own muscle, can all be converted to calorie, if needed
2) signal feed: it is long known that most cancers are addicted to glucose because of their preference for anaerobic metabolism, which is the basis for FDG-PET scan. This part of the cancer feed by sugar surge is dangerous, because it selects for hypoxic and invasive phenotype of cancer. So, in practical term, sure way for cancer patients to expire quickly is to feed them dunken doughnuts every day.
my fault -
所有跟帖:
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怎么signal?为什么正常细胞不被signal?signal与三大营养物质代谢的三羧酸循环无关?
-闽姑-
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12/08/2009 postreply
19:44:05
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some known mechanism
-jaydad-
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12/08/2009 postreply
20:42:03
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谢谢详细解释.理解了你提供的mechanism.问题是要到多少糖量
-闽姑-
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12/09/2009 postreply
06:20:10