Treatment decisions are based on the LDL cholesterol, and the patient's risk factor profile (including the HDL cholesterol level) and estimated 10-year risk. Patients in the intermediate-risk group (two or more risk factors) are selected for diet therapy (therapeutic lifestyle changes) if LDL cholesterol is greater than 130 mg/dL. If the 10-year risk of CHD is < 10%, drug treatment is recommended if LDL is > 160 mg/dL; if the 10-year CHD risk is between 10% and 20%, drug treatment is recommended if LDL is > 130 mg/dL. Low-risk individuals with one or no risk factors and estimated 10-year CHD risk less than 10% are selected for diet therapy if LDL cholesterol is greater than 160 mg/dL and for drug therapy if it is greater than 190 mg/dL