新加坡说他们的基因编辑雄蚊计划成功了

Singapore's gene-edited mosquito program, Project Wolbachia, has achieved significant success, leading to a 75% reduction in dengue infection rates and an 80-90% reduction in Aedes aegypti mosquito populations in study areas. The program involves releasing male mosquitoes carrying the Wolbachia bacterium to suppress the wild mosquito population and has been expanded to cover more households due to these positive outcomes.
 

 

Key Outcomes of Project Wolbachia 

 

• Reduced Dengue Cases:

  A multi-site field study showed that residents in study areas are 75% less likely to be infected with dengue.
• Suppressed Mosquito Population:

  The introduction of Wolbachia-infected male mosquitoes has led to an 80-90% reduction in the local Aedes aegypti mosquito population in the release sites.
• Spillover Effect:

  The release of male mosquitoes can also reduce mosquito populations and dengue infections in adjacent areas through a spillover effect, where released mosquitoes mate with local females, reducing egg hatching.
• Expansion of the Program:

  Following these promising results, The National Environment Agency (NEA) is expanding Project Wolbachia to cover more households.

How it Works

• Wolbachia Bacteria:

  The program uses Aedes aegypti mosquitoes infected with the naturally occurring Wolbachia bacterium. 

   
• Reproductive Sterility:

  When male Wolbachia-infected mosquitoes are released and mate with wild female mosquitoes, the resulting eggs do not hatch, leading to a reduction in the mosquito population. 

   
• Population Control:

  This strategy effectively suppresses the population of the Aedes aegypti mosquito, which is the primary vector for dengue. 

   

Overall Impact

Project Wolbachia is seen as a promising and sustainable method for controlling dengue in Singapore by reducing mosquito populations and the incidence of the disease. 

 

 

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