我的LDL高,做了Lp(a) and ApoB, 这两个都正常,所以对高一点的LD L就不是太担心了。
The Lp(a) (lipoprotein(a)) and ApoB (apolipoprotein B) blood tests measure specific lipoproteins that help assess cardiovascular risk beyond traditional cholesterol tests. Here’s an explanation of each:
Lp(a) Test
• What It Measures: Lipoprotein(a), a type of LDL (“bad” cholesterol) with an additional protein called apolipoprotein(a).
• Why It’s Important: Elevated Lp(a) levels are associated with an increased risk of atherosclerosis, heart attack, and stroke, regardless of other cholesterol levels.
• Genetic Component: Lp(a) levels are primarily determined by genetics, so lifestyle changes or medications may have limited impact on reducing it.
• Who Should Test: People with a family history of early cardiovascular disease, unexplained high cholesterol, or personal history of heart disease.
ApoB Test
• What It Measures: Apolipoprotein B, the main protein in atherogenic lipoproteins like LDL and VLDL (very low-density lipoprotein).
• Why It’s Important: ApoB reflects the total number of atherogenic particles in the blood, which may be a better indicator of cardiovascular risk than LDL-C alone.
• Significance: High ApoB levels mean more particles that can penetrate artery walls and cause plaque buildup, increasing cardiovascular disease risk.
• Who Should Test: Individuals with high LDL, diabetes, obesity, or a strong family history of heart disease.
Comparison and Use in Risk Assessment
• Both tests provide a more comprehensive view of cardiovascular risk when combined with traditional lipid panels.
• Lp(a) helps identify genetic risk, while ApoB measures the total burden of cholesterol-carrying particles.