PAXLOVID 用于治疗12 岁以上体重至少 88 磅,轻度至中度 COVID-19.

https://sharedsystems.dhsoha.state.or.us/DHSForms/Served/ln4029e.pdf

https://www.fda.gov/media/155051/download

Who should generally not take PAXLOVID?

Do not take PAXLOVID if:

• You are allergic to nirmatrelvir, ritonavir, or any of the ingredients in PAXLOVID.

• You are taking any of the following medicines:

Alfuzosin

Pethidine, piroxicam, propoxyphene

Ranolazine

Amiodarone, dronedarone, flecainide, propafenone, quinidine

Colchicine

Lurasidone, pimozide, clozapine

Dihydroergotamine, ergotamine, methylergonovine

Lovastatin, simvastatin

Sildenafil (Revatio®) for pulmonary arterial hypertension (PAH)

Triazolam, oral midazolam

Apalutamide

Carbamazepine, phenobarbital, phenytoin

Rifampin

St. John’s Wort (hypericum perforatum)

What are the important possible side effects of PAXLOVID?

Possible side effects of PAXLOVID are:

• Liver Problems. Tell your healthcare provider right away if you have any of

these signs and symptoms of liver problems: loss of appetite, yellowing of your

skin and the whites of eyes (jaundice), dark-colored urine, pale colored stools

and itchy skin, stomach area (abdominal) pain.

• Resistance to HIV Medicines. If you have untreated HIV infection, PAXLOVID

may lead to some HIV medicines not working as well in the future.

• Other possible side effects include:

 altered sense of taste

 diarrhea

 high blood pressure

 muscle aches

These are not all the possible side effects of PAXLOVID. Not many people have taken

PAXLOVID. Serious and unexpected side effects may happen. PAXLOVID is still being

studied, so it is possible that all of the risks are not known at this time.

 

 

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