研究：mRNA疫苗的加强针可以产生强大的中和Omicron新冠变体的能力 (ZT)

USA Today

• The best antibody protection came from a two-dose series of one of the mRNA vaccines, either Pfizer-BioNTech or Moderna, followed by an mRNA booster.
• A COVID-19 booster shot created “substantially higher” antibodies than vaccination followed by omicron infection, according to the Cell study published this week.
• Johnson & Johnson vaccine recipients, even with an mRNA booster, didn’t get the “breadth of response” of people with three mRNA doses, the study found.

Cell

The SARS-CoV-2 Omicron variant harbors 34 mutations in the spike, more than other variants

Two doses of mRNA-based vaccines elicit poor neutralization of Omicron

Three mRNA vaccine doses elicit potent variant crossneutralization, including Omicron

The Omicron pseudovirus infects cells more efficiently than other SARS-CoV-2 variants