怪不得日本的骨质疏松患者如此之多

 

Epidemiology of osteoporosis in Japan，Clin Calcium. 2012 Jun;22(6):797-803.

摘要，机器翻译如下：

相关骨折的高患病率和悲剧性后果使骨质疏松症成为现代社会的主要负担。根据基于人群的流行病学研究，日本骨质疏松症的估计人数为 1500 万，其中只有 20% 正在接受治疗。骨质疏松症是一种高度治疗不足的疾病。 2007 年日本髋部骨折的最新发病率为万分之 5.1 和万分之 18.1，患者人数约为 13 万人，比 1987 年的初步调查高出 2.8 倍，但仍处于大大低于高加索人群的比率。这种发病率的增加可以用老年人口的增加来解释。与髋部骨折相比，日本椎骨骨折患病率和发病率的数据含糊不清。据报道，椎骨骨折的患病率与白人人群相当，甚至更高，70 多岁的女性约为 30%，80 多岁的女性约为 40%。在指数骨折后的一年内，髋部骨折会使死亡风险增加约 10% 或 20%。 60%的髋部骨折患者功能水平较骨折前下降。即使在放射学确定的情况下，椎骨骨折也会增加死亡风险。我们目前在日本有 1300 万骨质疏松症患者，其中每年有 13 万人患有髋部骨折，其中 2 万人死亡，6 万人出现功能衰退。应以更有效的方式对骨质疏松症采取有效的预防和治疗措施。预计新指南将比以往任何时候都发挥更大的作用，以促进预防骨质疏松症的措施并提高医生对这种疾病的认识。

Abstract

The high prevalence and tragic consequences of related fractures make osteoporosis a major burden on modern society. According to population-based epidemiologic studies, the estimated number of people with osteoporosis in Japan is 15 million, and only 20% of them are under treatment. Osteoporosis is a highly undertreated disease. The most recent incidence rates of hip fracture in Japan were 5.1 in 10,000 men and 18.1 in 10,000 women in 2007, and the number of patients are approximately 130 thousands which are 2.8-fold higher than those of the initial survey of 1987, but are still substantially less than rates in Caucasian populations. This increase in incidence rates can be explained by an increase in the elderly population. Data on the prevalence and incidence of vertebral fractures in Japan are vague compared with those of hip fracture. Prevalence rate of vertebral fracture was reported to be comparable to those in Caucasian populations, or even higher, and is approximately 30% in women aged 70s and 40% in those aged 80s. Hip fracture increases the mortality risk by approximately 10% or 20% during one year after the index fracture. Functional level of patients with hip fracture is deteriorated in 60% of them compared with pre-fracture level. Vertebral fracture also increases the risk of mortality even in radiographically determined ones. We currently have 13 million patients with osteoporosis in Japan among whom 130 thousands are suffered from hip fracture every year among whom 20 thousands die and 60 thousands experience functional decline. Effective preventive and therapeutic measures for osteoporosis should be conducted in more efficient ways. A greater role of the new guideline is expected than ever to promote preventive measures against osteoporosis and to increase physician's awareness to this disease.

所有跟帖： 

• 寿命长的原因。 -DSc- ♂ (0 bytes) () 12/14/2021 postreply 10:52:21