慢性乙肝很难治愈，只能控制。网站不同说法大致相同。对于治愈，不同学术网站也有不同的说法，取决于它们各自的定义。
1.Cleavland clinic:
"How do you get chronic hepatitis B?
Chronic hepatitis B develops when your immune system fails to fight off the virus. Most people successfully fight it off during the acute phase of the infection. The acute phase is when your immune system recognizes the virus and launches its attack."
https://my.clevelandclinic.org/health/diseases/4246-hepatitis-b
2. 维基百科
"婴儿经由母亲垂直感染B型肝炎后，有90%的机率成为慢性B型肝炎带原者；而5岁后才感染B型肝炎者，长大后只有不到10%会成为慢性带原者[4]。虽然大部分慢性肝炎患者没有症状，但却有机会发展为肝硬化甚至肝癌[2]，亦为慢性肝炎患者死因的15%至25%[1]。"
3. 对于治愈也有不同的定义：1）根除行治愈（没有乙肝DNA）， 2）临床治愈，没有症状，血清HbsAg 长期阴性。
4. 这是一份44个乙肝住院病人的5年追踪报告，41个病人清除了表面抗原 ，3/44(6.8%)转为慢性感染
Long-Term Follow-Up of Acute Hepatitis B: New Insights in Its Natural History and Implications for
Antiviral Treatment
3.2. Clinical Outcome, Natural History and HBsAg Clearance
All 75 patients were cared for as inpatients for a few days on supportive treatment: Hydration, glucose, and electrolytic balance. Three patients with particularly high levels of liver damage were treated with entecavir until anti-HBsAg seroconversion. After clinical improvement, all patients were discharged, and most were further followed at the same center as outpatients. Clinical data recorded during the hospital stay or collected during follow-up visits were analyzed for the study. None of the patients reported or were documented as having been vaccinated. Twenty-six patients were lost during follow-up after a short hospital stay, 49 were followed as outpatients for a variable amount of time. Of these, 44 were followed to HBsAg clearance or for longer than five years. For the purposes of this study, HBsAg clearance was defined as the intermediate time between the last positive and the first negative result. By this definition, 36/44 patients cleared HBsAg within six months (Rapid Resolvers, RR), as shown in Figure 2A. Of the other eight (Slow Resolvers, SR), three (3/44, 6.8%) developed a true chronic HBeAg+ infection (>4 years now, two of them requiring chronic antiviral treatment). SR were infected with: Four genotype A, two genotype F, and one of genotype D and B respectively. Of these, two genotype A and one genotype B infections became chronic. Genotype D infection in adults showed the lowest probability of lasting longer than six months (6.7% vs. 22% non–D genotypes, not significant).
