脂溶和水溶的成分都有作用。仅仅是水溶的恐怕效果不是最好的。这似与青蒿素类似。

 

Zhong Yao Cai. 1998 Sep;21(9):462-6.

[Effects of herba Pogostemonis on gastrointestinal tract].

[Article in Chinese]

Chen X¹, He B, Li X, Luo J.

Author information

1

Guangdong College of Pharmacy, Guangzhou 510224.

Abstract

The effects of the three extracts (Decoction, oil-free decoction and volatile oil) of Herba Pogostemonis on gastrointestinal tract were studied. The results showed that all the three extracts inhibited the automatic contraction and Ach, BaCl2-induced spasmodic contraction of isolated rabbit intestine, among the three extracts the volatile oil was the most potent. In vivo the decoction and the oil-free decoction could depress gastric evacuation and inhibit the normal and neostigmine-induced intestinal propellent movement in mice, but the volatile oil could not. The decoction and the oil-free decoction also increased gastric secretion of acid and activity of pepsin and amylase. Furthermore, the decoction and the oil-free decoction reduced the incidence of diarrhea induced by senna but volatile oil enhanced cooperatively. All the three extracts relieved the gripping pain induced by abdominal administration of acetic acid, and the effect of decoction was more potent that the others. The above results revealed that the effective components of Herba Pogostemonis may be mainly water-solube.

PMID:

12569839