此R非彼R。这种移花接木、瞒天过海的事你也信?

来源: fuz 2021-03-09 10:02:47 [] [博客] [旧帖] [给我悄悄话] 本文已被阅读: 次 (1942 bytes)
本文内容已被 [ fuz ] 在 2021-03-09 10:23:19 编辑过。如有问题,请报告版主或论坛管理删除.

知道人体内有多少种mRNA么?

https://www.qiagen.com/us/resources/faq?id=06a192c2-e72d-42e8-9b40-3171e1eb4cb8&lang=en

How much RNA does a typical mammalian cell contain? 
FAQ ID -2946

 

The RNA content and RNA make up of a cell depend very much on its developmental stage and the type of cell. To estimate the approximate yield of RNA that can be expected from your starting material, we usually calculate that a typical mammalian cell contains 10–30 pg total RNA. 

The majority of RNA molecules are tRNAs and rRNAs. mRNA accounts for only 1–5% of the total cellular RNA although the actual amount depends on the cell type and physiological state. Approximately 360,000 mRNA molecules are present in a single mammalian cell, made up of approximately 12,000 different transcripts with a typical length of around 2 kb. Some mRNAs comprise 3% of the mRNA pool whereas others account for less than 0.1%. These rare or low-abundance mRNAs may have a copy number of only 5–15 molecules per cell.

 

所有跟帖: 

谢谢夫子解惑,不过还是没明白,没觉得和文章内容矛盾啊? -nowayitsover- 给 nowayitsover 发送悄悄话 nowayitsover 的博客首页 (94 bytes) () 03/09/2021 postreply 16:22:05

主贴第一句是啥意思?:“ mRNA 疫苗的作用,把mRNA释放出来了,可能增加癌症风险”。你这么写,不是张冠李戴,误导大众么? -fuz- 给 fuz 发送悄悄话 fuz 的博客首页 (0 bytes) () 03/09/2021 postreply 16:26:28

OK,我改一下,原先说的不对。 -nowayitsover- 给 nowayitsover 发送悄悄话 nowayitsover 的博客首页 (0 bytes) () 03/09/2021 postreply 16:48:17

上面回帖里已经讲得很明白了,每个细胞中有成千上万种mRNA, 各有个的作用,怎么可以混为一谈 -fuz- 给 fuz 发送悄悄话 fuz 的博客首页 (0 bytes) () 03/09/2021 postreply 16:39:19

仔细读了一下,文章的作者问的是这个注射进去的mRNA会不会致癌,他的逻辑是一般的mRNA都有致癌作用。 -nowayitsover- 给 nowayitsover 发送悄悄话 nowayitsover 的博客首页 (0 bytes) () 03/09/2021 postreply 16:55:51

我觉得文章里的这个问题很valid,只是现在不可能有答案。 -nowayitsover- 给 nowayitsover 发送悄悄话 nowayitsover 的博客首页 (0 bytes) () 03/09/2021 postreply 21:28:16

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