大家对Angelina Jolie的乳腺癌预防手术怎么看？

有必要么？

http://www.cnn.com/2013/05/14/showbiz/angelina-jolie-double-mastectomy/index.html?hpt=hp_t1

(CNN) -- Actress Angelina Jolie announced in a New York Times op-ed article on Tuesday that she underwent a preventive double mastectomy after learning she carries a mutation of the BRCA1 gene, which sharply increases her risk of developing breast cancer and ovarian cancer.

"My doctors estimated that I had an 87 percent risk of breast cancer and a 50 percent risk of ovarian cancer, although the risk is different in the case of each woman," Jolie wrote. "Once I knew that this was my reality, I decided to be proactive and to minimize the risk as much I could. I made a decision to have a preventive double mastectomy."

Jolie's mother, actress and producer Marcheline Bertrand, died of ovarian cancer in 2007 at the age of 56. Jolie is 37 years old.

In the Times op-ed, titled "My Medical Choice," Jolie said she finished three months of medical procedures at the Pink Lotus Breast Center in California on April 27 that included the mastectomies and reconstruction.

Opinion: Jolie's choice carries risks with benefits

A mastectomy is an operation that removes all or part of the breast.

Jolie: 'I've decided to be proactive'

CNN anchor: I have breast cancer

Explaining Jolie's cancer gene

CNN archives: Jolie on her mom's cancer

Photos: Life of Angelina Jolie

She wrote that her experience involved a three-step process. On February 2, the actress had a procedure that increases the chance that the nipple can be saved. Two weeks later, she had major surgery where the breast tissue was removed and temporary fillers were put in place. Nine weeks later she described undergoing "reconstruction of the breasts with an implant."

"There have been many advances in this procedure in the last few years," she said, "and the results can be beautiful."

Why double mastectomies are up

"I wanted to write this to tell other women that the decision to have a mastectomy was not easy. But it is one I am very happy that I made," Jolie wrote. "My chances of developing breast cancer have dropped from 87 percent to under 5 percent."

BRCA stands for breast cancer susceptibility genes -- a class of genes known as tumor suppressors, according to the National Cancer Institute.

Hollywood applauds Jolie for going public with surgery

Mutations of the BRCA1 and BRCA2 genes have been linked to hereditary breast and ovarian cancer. A blood test can determine if a woman is "highly susceptible" to the cancers.

Fellow actress Christina Applegate had a similar procedure in 2008. She also had a mutation of the BRCA1 gene.

所有跟帖： 

• 我比较同意一位读者的观点 -闲情- ♀ (4662 bytes) () 05/14/2013 postreply 09:18:39

• 可以用肚子上的脂肪隆乳。 不是非得用硅胶。 -如尘- ♀ (0 bytes) () 05/14/2013 postreply 12:20:01

• Jolie 肚子上好像没啥脂肪：） -viewfinder- ♀ (0 bytes) () 05/14/2013 postreply 13:18:56

• 多采用背阔肌瓣带蒂转移术 -御用文人- ♀ (0 bytes) () 05/14/2013 postreply 17:41:02

• 个人认为不推荐！把乳腺全部切除没留一个乳腺细胞是很难的！ -回家路- ♂ (0 bytes) () 05/14/2013 postreply 09:35:24

• 都是被假科学忽悠的。不过帮助了美国的GDP.就是因为这些花费,美国的GDP的1/3是医疗行业提供的。 -薛成- ♂ (0 bytes) () 05/14/2013 postreply 09:38:14

• 你太偏激了。这个不是假科学是真科学。 -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 11:05:48

• 那么，生活质量就不用考虑了？ -薛成- ♂ (0 bytes) () 05/14/2013 postreply 18:44:28

• 她的医生应该和她讨论过这个问题 -TBz- ♂ (82 bytes) () 05/15/2013 postreply 09:24:15

• 科学过头了！真是基因缺陷要致癌的话，乳腺切了不能长了，还得在其它地方长，不是更不好治？ -福娃2009- ♀ (0 bytes) () 05/15/2013 postreply 08:38:15

• 她的医生认为她有90%几率得乳腺癌，切除了就几乎为零几率。可以理解她的选择。 -viewfinder- ♀ (101 bytes) () 05/14/2013 postreply 10:26:40

• 今天中午和我先生一起吃饭我们谈起她 -Bluebell- ♀ (227 bytes) () 05/14/2013 postreply 11:04:53

• 这个真不是个容易的选择，就是在医学界也有争议。 -viewfinder- ♀ (282 bytes) () 05/14/2013 postreply 11:18:13

• 如果是你得了 -蒙城一郎中- ♂ (226 bytes) () 05/14/2013 postreply 12:12:41

• 郎中啊！你终于出现啦！：）））） -Bluebell- ♀ (249 bytes) () 05/14/2013 postreply 12:26:47

• 如果你老公 -蒙城一郎中- ♂ (314 bytes) () 05/14/2013 postreply 12:46:25

• 不理解你的逻辑. 老公没有注意到老婆的身体健康, 也不该把JJ切掉啊. -永远是中国人- ♂ (65 bytes) () 05/14/2013 postreply 12:53:17

• 逻辑. 老公把JJ切掉啊，也能预防JJ癌 -蒙城一郎中- ♂ (0 bytes) () 05/14/2013 postreply 12:54:11

• 搬马扎磕瓜子等着看郎中挨砸 ：）） -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 12:59:27

• 凭什么挨砸 ：）） -蒙城一郎中- ♂ (52 bytes) () 05/14/2013 postreply 13:01:28

• 为什么不砸你 -Bluebell- ♀ (121 bytes) () 05/14/2013 postreply 13:03:35

• 砸我才没天理咧 -蒙城一郎中- ♂ (222 bytes) () 05/14/2013 postreply 13:06:22

• 人法地 地法天 天法道 道法自然 -Bluebell- ♀ (173 bytes) () 05/14/2013 postreply 13:24:03

• 这就你的不科学了哈～ -蒙城一郎中- ♂ (428 bytes) () 05/14/2013 postreply 13:38:17

• 郎中今天这么文青哈～ -Bluebell- ♀ (186 bytes) () 05/14/2013 postreply 13:59:07

• 抱下抱下，咱俩不打架 ：））））） -Bluebell- ♀ (190 bytes) () 05/14/2013 postreply 12:57:15

• 我阿姨婚姻幸福得很，乳癌去年走了。 -如尘- ♀ (0 bytes) () 05/14/2013 postreply 12:41:53

• 回复：大家对Angelina Jolie的乳腺癌预防手术怎么看？ -周游列国逍遥人生- ♂ (36 bytes) () 05/14/2013 postreply 10:28:57

• 是的，日本女人移民到美国后，乳腺癌发病率增加10倍以上！饮食环境因素也是很重要的！ -回家路- ♂ (0 bytes) () 05/14/2013 postreply 10:53:54

• BRCA1基因，科学研究证实是遗传的。 -TBz- ♂ (0 bytes) () 05/14/2013 postreply 13:00:53

• 得癌几率87%,这个基因当然不是100%绝对生效的 -TBz- ♂ (0 bytes) () 05/14/2013 postreply 15:04:48

• 能做出这样的决定需要勇气，尤其是她妈和她外婆都早逝，她又有87%的发病几率 -tiger00- ♀ (137 bytes) () 05/14/2013 postreply 11:49:10

• “双侧切了还肺癌脑癌的”，那还得预先切肺切脑？癌症因素不去除，切哪也没用。 -ooopsss- ♂ (0 bytes) () 05/14/2013 postreply 12:00:00

• in her case, the probability is reduced from 87% to 5%. -如尘- ♀ (0 bytes) () 05/14/2013 postreply 12:23:27

• agree -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 12:29:09

• 美国人很相信概率数字。 但是有几个人真正明白概率是什么，怎么解读那个数字？ -lavendar99- ♀ (149 bytes) () 05/14/2013 postreply 12:32:20

• 是应该认真解读这个数字。87%是life time患乳腺癌几率， -viewfinder- ♀ (460 bytes) () 05/14/2013 postreply 13:09:18

• 这个，也需要这样解读，有乳腺，就有可能生乳癌，不分男女。没有乳腺，何来乳癌？此概率为0。。。因此，推动另外1种人类之思。 -大江川- ♂ (0 bytes) () 05/14/2013 postreply 15:42:26

• 九成得癌的机会还不切除？为什么拿性命赌？我觉得明智 -ECityBlues- ♀ (185 bytes) () 05/14/2013 postreply 12:47:19

• 拼命点头，对对对 -Bluebell- ♀ (48 bytes) () 05/14/2013 postreply 13:00:49

• 而且， 孩子生完了， 那啥本来也木啥用 ， 对吧 ：） -如尘- ♀ (0 bytes) () 05/14/2013 postreply 13:06:13

• 但她的mammogram现在肯定正常！她也可能一辈子根本不会得癌。对个人来说，机率要么0%, 要么100%. -回家路- ♂ (0 bytes) () 05/14/2013 postreply 13:21:26

• 她有87%的可能100%得癌 -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 13:25:48

• 她一辈子不得癌的几率１３％， 得癌的几率８７％。 -如尘- ♀ (0 bytes) () 05/14/2013 postreply 13:36:09

• 是的，按着整体概率她真该切，但马上切不切还有很大争议！因为还有其他选择！ -回家路- ♂ (0 bytes) () 05/14/2013 postreply 13:40:25

• 刚问了诊所的一个年轻女孩，她是积极赞成的，她说，女士要做breast plant anyway! -回家路- ♂ (0 bytes) () 05/14/2013 postreply 13:46:02

• 那不是还要做chemo？ 我一个做过chemo的朋友说： -如尘- ♀ (36 bytes) () 05/15/2013 postreply 07:37:13

• 完全同意！其实文章没说，即使切掉也要密切监测！还有机会在局部得的！ -回家路- ♂ (0 bytes) () 05/15/2013 postreply 08:46:57

• 这个是人家的选择，怎么看也没用，反正不犯法。爱咋咋地。 -Déjàvu116- ♀ (0 bytes) () 05/14/2013 postreply 16:08:52

• 高危不代表准得病，只是个统计数字罢了。 -Déjàvu116- ♀ (204 bytes) () 05/14/2013 postreply 16:13:01

• 把能切的都切了，神经该有问题了～～～～ -lavendar99- ♀ (0 bytes) () 05/14/2013 postreply 17:20:40

• 哈哈哈，含蓄点儿。。。 -Déjàvu116- ♀ (0 bytes) () 05/14/2013 postreply 17:21:44

• Talk to Genetic Counselors -tiaa-cref- ♂ (0 bytes) () 05/14/2013 postreply 16:09:30

• Talk to Genetic Counselors -tiaa-cref- ♂ (246 bytes) () 05/14/2013 postreply 16:10:32

• 不觉得是最好的选择！！ -Déjàvu116- ♀ (0 bytes) () 05/14/2013 postreply 16:14:11

• 洗耳恭听，您给说说最好的选择是啥？ -Bluebell- ♀ (0 bytes) () 05/14/2013 postreply 18:05:09

• 弄个假的没有刺激感觉，多活几年又有什么意思？-〉钱多撑的。 -faday- ♀ (0 bytes) () 05/14/2013 postreply 16:45:05

• 你肯定不是当妈的。。。。 -Bluebell- ♀ (62 bytes) () 05/14/2013 postreply 18:06:51

• 乳腺癌预防手术有一点aggressive,但可以理解. -Lilac2003- ♀ (0 bytes) () 05/15/2013 postreply 08:28:27

• 即使切掉后，也要close follow up. 只是得的机会少了，但还会在局部得！并不是全放下心来！ -回家路- ♂ (0 bytes) () 05/15/2013 postreply 08:42:17