Why is alcohol so harmful?
Scientists think that the main way alcohol causes health problems is by damaging DNA. When you drink alcohol, your body metabolizes it into acetaldehyde, a chemical that is toxic to cells. Acetaldehyde both “damages your DNA and prevents your body from repairing the damage,” Dr. Esser explained. “Once your DNA is damaged, then a cell can grow out of control and create a cancer tumor.”
Alcohol also creates oxidative stress, another form of DNA damage that can be particularly harmful to the cells that line blood vessels. Oxidative stress can lead to stiffened arteries, resulting in higher blood pressure and coronary artery disease.
“It fundamentally affects DNA, and that’s why it affects so many organ systems,” Dr. Naimi said. Over the course of a lifetime, chronic consumption “damages tissues over time.”