蒿甲醚的活性是青蒿素的6倍。

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Artemether

From Wikipedia, the free encyclopedia
 
 
Artemether
Artemether.svg
Systematic (IUPAC) name
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]-2-benzopyran
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.
Legal status
Routes Oral
Identifiers
CAS number 71963-77-4 
ATC code P01BE02
PubChem CID 68911
DrugBank DB06697
ChemSpider 62138 Yes
UNII C7D6T3H22J Yes
KEGG D02483 Yes
ChEBI CHEBI:195280 Yes
ChEMBL CHEMBL1237051 
Chemical data
Formula C16H26O5 
Mol. mass 298.374 g/mol
  (what is this?)  (verify)

Artemether (INN) is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria. Its combination (coformulation) withLumefantrine has first been marketed by Novartis under the brand names Riamet and Coartem. Today, this combination therapy is available as generic from several manufacturers.

It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.[1]

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