粪便菌群移植（FMT）
也被称为粪便移植[1]是从健康个体的粪便细菌的移植过程进入受体[2]已被证明是一种非常有效的治疗的患者的艰难梭菌患感染（CDI），其产生的效果，从腹泻的伪膜性肠炎。[3]从2000年开始，艰难梭菌的高毒性菌株已经出现，这似乎是链接到在经验性治疗常用的抗生素。[4]仅在美国，估计有300万新的急性难辨梭状芽孢杆菌感染，目前每年诊断。[5]其中，一个小组将继续发展暴发型CDI导致每天约300人死亡或每年将近110,000人死亡。由于在北美和欧洲的疫情，FMT已经获得了日益突出，一些专家呼吁它成为第一线治疗手段。
上一页方面的程序，包括粪便bacteriotherapy，粪便输血，粪便移植，移植粪便，粪便灌肠和人类的益生菌输液（HPI）。因为程序涉及到整个粪便菌群，而不仅仅是一个单一药剂或药剂组合的完全恢复，这些术语现在已经换成了新的术语“粪便菌群移植”。[2] FMT涉及通过恢复结肠菌群通过输液大便引入健康的菌群，如通过灌肠，从一个健康的人供体获得的。
从健康供体粪便输液被证明在随机对照试验可用于治疗复发性艰难梭菌，并比单独使用万古霉素更有效高度有效的。[8] [9]它也可以用于治疗其他条件，包括结肠炎，便秘，肠易激综合征，和某些神经系统疾病。
Fecal microbiota transplantation (FMT) also known as a stool transplant[1] is the process of transplantation of fecal bacteria from a healthy individual into a recipient.[2] It has been proven to be a highly effective treatment for patients suffering from Clostridium difficile infection (CDI), which produces effects ranging from diarrhea to pseudomembranous colitis.[3] Beginning in 2000, hypervirulent strains of C. difficile have emerged, which seem to be linked to antibiotics that are commonly used in empiric treatments.[4] In the U.S alone, an estimated 3 million new acute Clostridium difficile infections are currently diagnosed annually.[5] Of these, a subgroup will go on to develop fulminant CDI which results in approximately 300 deaths per day or almost 110,000 deaths per year.[6] Due to the epidemic in North America and Europe, FMT has gained increasing prominence, with some experts calling for it to become first-line therapy for CDI.[7]
Previous terms for the procedure include fecal bacteriotherapy, fecal transfusion, fecal transplant, stool transplant, fecal enema and human probiotic infusion (HPI). Because the procedure involves the complete restoration of the entire fecal microbiota, not just a single agent or combination of agents, these terms have now been replaced by the new term 'Fecal Microbiota Transplantation'.[2] FMT involves restoration of the colonic flora by introducing healthy bacterial flora through infusion of stool, e.g. by enema, obtained from a healthy human donor.
Infusion of feces from healthy donors was demonstrated in a randomized, controlled trial to be highly effective in treating recurrent C. difficile, and more effective than vancomycin alone.[8][9] It can also be used to treat other conditions, including colitis,[10] constipation,[10] irritable bowel syndrome,[10] and some neurological conditions。
Source：http://en.wikipedia.org/wiki/Fecal_bacteriotherapy
也被称为粪便移植[1]是从健康个体的粪便细菌的移植过程进入受体[2]已被证明是一种非常有效的治疗的患者的艰难梭菌患感染（CDI），其产生的效果，从腹泻的伪膜性肠炎。[3]从2000年开始，艰难梭菌的高毒性菌株已经出现，这似乎是链接到在经验性治疗常用的抗生素。[4]仅在美国，估计有300万新的急性难辨梭状芽孢杆菌感染，目前每年诊断。[5]其中，一个小组将继续发展暴发型CDI导致每天约300人死亡或每年将近110,000人死亡。由于在北美和欧洲的疫情，FMT已经获得了日益突出，一些专家呼吁它成为第一线治疗手段。
上一页方面的程序，包括粪便bacteriotherapy，粪便输血，粪便移植，移植粪便，粪便灌肠和人类的益生菌输液（HPI）。因为程序涉及到整个粪便菌群，而不仅仅是一个单一药剂或药剂组合的完全恢复，这些术语现在已经换成了新的术语“粪便菌群移植”。[2] FMT涉及通过恢复结肠菌群通过输液大便引入健康的菌群，如通过灌肠，从一个健康的人供体获得的。
从健康供体粪便输液被证明在随机对照试验可用于治疗复发性艰难梭菌，并比单独使用万古霉素更有效高度有效的。[8] [9]它也可以用于治疗其他条件，包括结肠炎，便秘，肠易激综合征，和某些神经系统疾病。
Fecal microbiota transplantation (FMT) also known as a stool transplant[1] is the process of transplantation of fecal bacteria from a healthy individual into a recipient.[2] It has been proven to be a highly effective treatment for patients suffering from Clostridium difficile infection (CDI), which produces effects ranging from diarrhea to pseudomembranous colitis.[3] Beginning in 2000, hypervirulent strains of C. difficile have emerged, which seem to be linked to antibiotics that are commonly used in empiric treatments.[4] In the U.S alone, an estimated 3 million new acute Clostridium difficile infections are currently diagnosed annually.[5] Of these, a subgroup will go on to develop fulminant CDI which results in approximately 300 deaths per day or almost 110,000 deaths per year.[6] Due to the epidemic in North America and Europe, FMT has gained increasing prominence, with some experts calling for it to become first-line therapy for CDI.[7]
Previous terms for the procedure include fecal bacteriotherapy, fecal transfusion, fecal transplant, stool transplant, fecal enema and human probiotic infusion (HPI). Because the procedure involves the complete restoration of the entire fecal microbiota, not just a single agent or combination of agents, these terms have now been replaced by the new term 'Fecal Microbiota Transplantation'.[2] FMT involves restoration of the colonic flora by introducing healthy bacterial flora through infusion of stool, e.g. by enema, obtained from a healthy human donor.
Infusion of feces from healthy donors was demonstrated in a randomized, controlled trial to be highly effective in treating recurrent C. difficile, and more effective than vancomycin alone.[8][9] It can also be used to treat other conditions, including colitis,[10] constipation,[10] irritable bowel syndrome,[10] and some neurological conditions。
Source：http://en.wikipedia.org/wiki/Fecal_bacteriotherapy
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