关于CRP，细菌，病毒的文献见内， 一家之说。。。

CRP文献特多， 自己不用打字，copy就好：）

https://www.google.com/#q=crp+increase+causes

in general, the main causes of increased CRP and other markers of inflammation are:

• burns,
• trauma,
• infections,
• inflammation,
• active inflammatory arthritis, and.
• certain cancers.

C-Reactive Protein (CRP): Get the Facts about This Test

www.medicinenet.com/c-reactive_protein_test_crp/article.htm

MedicineNet

http://www.ncbi.nlm.nih.gov/pubmed/8511515

Scand J Infect Dis. 1993;25(2):207-13.

C-reactive protein in viral and bacterial respiratory infection in children.

Korppi M¹, Kröger L.

Department of Paediatrics, Kuopio University Hospital, Finland.

Abstract

C-reactive protein (CRP) was studied in 209 children treated in hospital due to middle or lower respiratory tract infection with serologically demonstrated viral or bacterial aetiology. Of the 110 patients with serological evidence of bacterial infection, either alone or in association with viral infection, 52% had CRP > 20 mg/l, 35% > 40 mg/l and 15% > 80 mg/l. Of the 99 patients with serological evidence of viral infection alone, 35% had CRP > 20 mg/l, but only 12% > 40 mg/l and 5% > 80 mg/l. Nearly all, 88%, of the 25 patients with CRP > 40 mg/l in association with viral infection had either an infectious focus, specific microbial or non-specific laboratory evidence suggestive of bacterial infection. By calculating diagnostic parameters at 3 cut-off levels of CRP, the level 40 mg/l seemed more useful than 20 mg/l or 80 mg/l for differentiation between viral and bacterial infections. By using a CRP value of 40 mg/l as a screening limit sensitivity was 0.55, specificity 0.88, positive predictive value 0.76, negative predictive value 0.55, and likelihood ratios of a positive and negative test result 2.9 and 0.74, respectively. It is concluded that low CRP values do not rule out bacterial aetiology of respiratory infection in children. On the other hand viral infection without bacterial involvement is very improbable if CRP is > 40 mg/l. Our results suggest that high CRP values rule out viral infection as a sole aetiology of infection; bacterial infection and antibiotic treatment should be considered in these cases.

所有跟帖： 

• 谢谢，很有价值，学习了。 -吃与活- ♂ (0 bytes) () 01/28/2016 postreply 19:02:16

• 是没有。我猜教授是做研究用的，90年代CRP研究很火的。结论目前仍不错。。。 -志在千里- ♀ (173 bytes) () 01/28/2016 postreply 19:42:29

• 不过CRP用的挺多的。如文献说，有CRP值，感染经验治疗时也是参考。。。 -志在千里- ♀ (0 bytes) () 01/28/2016 postreply 19:50:20

• 是炎症的指示，对推断心血管疾病风险有价值。 -吃与活- ♂ (0 bytes) () 01/28/2016 postreply 20:02:34

• 对！是炎症的指示，对推断心血管疾病风险有价值。 -TBz- ♂ (0 bytes) () 01/28/2016 postreply 21:45:25

• 我的小孩以前常常是生病一开始检查不到衣原体，等厉害了才查得出。我就希望有简单的方法诊断细菌感染。谢谢各位讨论 -吃与活- ♂ (506 bytes) () 01/28/2016 postreply 19:50:51