有几个关键词没有highligh到，帮你补充一下。

See comment in PubMed Commons below

Curr Pharm Des. 2015 Nov 12. [Epub ahead of print]

Antiatherosclerotic and Cardioprotective Effects of Time-Released Garlic Powder Pills.

Karagodin VP¹, Sobenin IA, Orekhov AN.

Author information

• ¹Department of Commodity Research and Commodity Expertise, Faculty of Trade Economics and Commodity Science, Plekhanov Russian University of Economics, Moscow, Russia, Stremyanny per. 36, 117997. [e-mail].

Abstract

Garlic is believed to produce beneficial changes in different cardiovascular risk factors, thus possessing antiatherosclerotic properties. The hypotensive and cholesterol-lowering effects were investigated in two studies in men with mild arterial hypertension and in men with mild hypercholesterolemia. Eight-week treatment resulted in the reduction of both systolic and diastolic blood pressure by 5.2% (P=0.008) and 4.0% (P=0.014), respectively. In hypolipidemic study, the 12-week treatment resulted in a decrease in LDL cholesterol by 11.8% (P=0.002), while HDL cholesterol increased by 11.5% (P=0.013). In men with cerebral atherosclerosis it has been demonstrated that 14-days treatment inhibited ADP-induced platelet aggregation by 25.4% (P<0.05) and increased plasma fibrinolytic activity by 22.4% (P<0.05). One more study was performed in high-risk patients to evaluate the changes of prognostic cardiovascular risk that was calculated using algorithms derived from Framingham and Muenster Studies. Twelve-months treatment lowered 10-years prognostic risk of CHD by 13.2% in men (P=0.005), and by 7.1% in women (P=0.040). Ten-year prognostic risk of acute myocardial infarction and sudden coronary death was lowered by 26.1% in men (P=0.025). The Atherosclerosis Monitoring and Atherogenicity Reduction Study (AMAR) was designed to estimate the effect of two-year treatment with garlic powder pills on the progression of carotid atherosclerosis in asymptomatic men. A significant correlation has been revealed between the changes in blood serum atherogenicity and the changes in carotid intima-media thickness (r=0.144, P=0.045). Evidence obtained from these studies as well as series of double-blinded placebo-controlled clinical trials indicates that garlic powder pills are effective for prevention of cardiovascular disorders.

 

也就是说用了大蒜后，血压能够由140/95降到133/90，这个效果相对来说微不足道。

另外，最重要最有意义的数据是：使用大蒜降血压降血脂，是否能够真正有效地减少心梗以及中风的几率，可惜这篇文章并没有相关的数据，而只是通过一些模型做出的推算，所以其实用价值要大打几个折扣。