第三，显效剂量要和毒性和可耐受剂量比较。
谢谢你文中的信息，你很认真。但是我不能认同你的结论。
附：
板蓝根的研究mskcc网站有些总结。现在学术界似乎还未下结论。
http://www.mskcc.org/cancer-care/herb/isatis-root
Isatis root exerts immunostimulatory effects by enhancing reticuloendothelial system function (11). Sinigrin and indigo have been identified as the compounds responsible for potential SARS inhibition (4). Clemastanin B, a major lignan compound in isatis, targets viral endocytosis, uncoating, and nuclear export of viral ribonucleoproteins (5). A crude extract of isatis root prevented influenza virus attachment to cells and therefore viral replication, but was inactive against respiratory syncytial virus, adenovirus, parainfluenza virus and enterovirus (19). Another component of isatis root demonstrates dose-dependent anti-endotoxic effects on lipopolysaccharide-induced expression of membrane-organizing extension spike protein, a main endotoxin receptor (10). Alkaloids isolated from isatis can inhibit leukocyte function and reduce inflammatory response (20). One animal study found that indigo root extract reduced tissue injury, enhanced hematopoietic system recovery, modulated serum inflammatory cytokines, and improved severe enteropathy in whole body irradiated mice (13).
An in vitro study also found that an ethanol extract of isatis root had a dose-dependent cytotoxic effect against human leukemia HL-60 cells (9). Indirubin, an active component of isatis, inhibits cyclin-dependent kinases (CDKs) and prevents proliferation by arresting cells in the G2/M phase (3).
谢谢你文中的信息，你很认真。但是我不能认同你的结论。
附：
板蓝根的研究mskcc网站有些总结。现在学术界似乎还未下结论。
http://www.mskcc.org/cancer-care/herb/isatis-root
Isatis root exerts immunostimulatory effects by enhancing reticuloendothelial system function (11). Sinigrin and indigo have been identified as the compounds responsible for potential SARS inhibition (4). Clemastanin B, a major lignan compound in isatis, targets viral endocytosis, uncoating, and nuclear export of viral ribonucleoproteins (5). A crude extract of isatis root prevented influenza virus attachment to cells and therefore viral replication, but was inactive against respiratory syncytial virus, adenovirus, parainfluenza virus and enterovirus (19). Another component of isatis root demonstrates dose-dependent anti-endotoxic effects on lipopolysaccharide-induced expression of membrane-organizing extension spike protein, a main endotoxin receptor (10). Alkaloids isolated from isatis can inhibit leukocyte function and reduce inflammatory response (20). One animal study found that indigo root extract reduced tissue injury, enhanced hematopoietic system recovery, modulated serum inflammatory cytokines, and improved severe enteropathy in whole body irradiated mice (13).
An in vitro study also found that an ethanol extract of isatis root had a dose-dependent cytotoxic effect against human leukemia HL-60 cells (9). Indirubin, an active component of isatis, inhibits cyclin-dependent kinases (CDKs) and prevents proliferation by arresting cells in the G2/M phase (3).
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