去年医生给打的那一针是booster shot吗?孩子是何时做的滴度检查?是完成乙肝三针疫苗

来源: 闽姑 2014-08-20 15:53:24 [] [博客] [旧帖] [给我悄悄话] 本文已被阅读: 次 (3841 bytes)
本文内容已被 [ 闽姑 ] 在 2014-08-20 16:25:15 编辑过。如有问题,请报告版主或论坛管理删除.
回答: 提起来问闽姑----帖子淹下去了happyjoin2014-08-20 14:17:17


请问去年医生给打的那一针是booster shot吗?孩子是何时做的滴度检查?是完成乙肝三针疫苗的若干年后还是就在第三针乙肝疫苗后的一,两个月后测的滴度.如果是后者(马上在第三针乙肝疫苗后的一,两个月后测的滴度<10 mIU/mL,是要考虑重打三针的.但若是过了若干年后再测,抗体滴度<10 mIU/mL是很正常的,CDC目前不推荐注射加强针.认为
第三针乙肝疫苗后的一,两个月后测的post vaccination titer testing>10 mIU/mL,那是有免疫力的.一些研究文章也支持: 虽然抗体滴度下降,但一个人的免疫功能正常的话,健康者是可以靠自己的免疫力(免疫记忆)抵抗乙肝病毒的.只有那些免疫功能低下者和一些高风险人群(比如一些特定的医务人员(抽血员),共用针头滥用注射药物者或无保护的性工作者等...)才需要考虑重打三针系列.所以何时做孩子的post vaccination titer testing很关键.

抱歉,我不是专家,也不懂.必要时约看和咨询GI或Hepatologist专科医生.下面的两个链接我觉得不错,和你一起学习:


1. What Should I Know About a Hepatitis B Titer?

The Centers for Disease Control and Prevention (CDC) recommends HBV vaccination be given by intramuscular injection at 0, 1, and 6 months. Postvaccination testing is not a routine practice except for infants born to mothers with HBV, immune compromised persons, healthcare workers, and sex partners of persons with chronic HBV. For the adult, a titer should be drawn 1 to 2 months after completing the vaccination series. For infants born from HBV-positive mothers, the testing should be done 3 to 9 months after receiving the vaccination series.

The CDC does not currently recommend revaccination in persons with intact immune systems. However, there is a 15-year span after vaccination where antibodies decline but protection is still afforded (the so-called "immune memory"). If a person who took the series never had a test to check for immunity, it may be wise to assess for adequate hepatitis B surface antibody (HBsAb) levels, indicating protection against hepatitis B antigen (HBsAg). (HBsAg is a serologic marker that indicates that the person is actively infectious.) If the patient tests HBsAb negative, indicating a lack of protection from HBV infection, a second series is recommended.[2](重新打三针)

......

第二个链接共两页,有更详细的Q&A:

2. Hepatitis B Vaccination FAQ - Stanford University











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谢谢你。 -happyjoin- 给 happyjoin 发送悄悄话 happyjoin 的博客首页 (0 bytes) () 08/20/2014 postreply 17:22:03

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