唉，今年春，P、M相继声称己开发出对新变种的疫苗，并开始临试。然后……进宫了。

https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-initiate-study-part-broad-development

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Separately, in order to be prepared for any potential future strain changes, Pfizer and BioNTech are in ongoing discussions with regulatory authorities, including the U.S. Food and Drug Administration (FDA) and the European Medicines Agency, regarding a registration-enabling clinical study to evaluate a variant-specific vaccine having a modified mRNA sequence. This study would use a new construct of the Pfizer-BioNTech vaccine based on the B.1.351 lineage, first identified in South Africa. This could position the Companies to update the current vaccine quickly if the need arises to protect against COVID-19 from circulating strains.

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 “At the same time, we are making the right investments and engaging in the appropriate conversations with regulators to help position us to potentially develop and seek authorization for an updated mRNA vaccine or booster if needed.”

“Our proactive clinical development strategy aims to create the foundation today, that will enable us to address the challenges of tomorrow. We want to be prepared for different scenarios,” said Ugur Sahin, CEO and Co-founder of BioNTech. “Therefore, we will be evaluating a second booster in the current regimen as well as preparing for a potential rapid adaption of the vaccine to address new variants which might escape the current version of our mRNA-based vaccine. The flexibility of our proprietary mRNA vaccine platform allows us to technically develop booster vaccines within weeks, if needed.

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Covid-19 Vaccines Targeting Multiple Variants Are in the Works at Moderna, Novavax 

Researchers are trying to get ahead of variants like those identified in the U.K., South Africa and Brazil

https://www.wsj.com/articles/covid-19-vaccines-targeting-multiple-strains-are-in-the-works-11615374007

 

https://www.contagionlive.com/view/moderna-vaccine-offers-protection-against-new-covid-19-variants

 

所有跟帖： 

• 这是很clear的选择，推booster，而不是推新疫苗。推booster成本低，便于自己和政府管理。 -voiceofme- ♂ (0 bytes) () 12/02/2021 postreply 16:53:45

• 效果也许和新疫苗一样好 -voiceofme- ♂ (0 bytes) () 12/02/2021 postreply 16:55:06