乳腺癌我的理解和你的不一样：

说的是表达ccr5的癌细胞，如果用CCR5 inhibitors，可纺织扩散。。。

ZT:

 The expression of CCR5 is selectively induced during the cancer transformation process and is not expressed in normal breast or prostate epithelial cells. Approximately 50% of human breast cancer expressed CCR5, primarily in triple negative breast cancer. ^[17]  CCR5 inhibitors blocked the migration and metastasis of CCR5 expressing breast and prostate cancer cells, suggesting CCR5 may function as a new therapeutic target. ^[17][18][19] Recent studies suggest that CCR5 is expressed in a subset of cancer cells with characteristics of cancer stem cells which are known to drive therapy resistance and CCR5 inhibitors enhanced cell killing of current chemotherapy.^[20] is likely that CCR5 plays a role in inflammatory responses to infection, though its exact role in normal immune function is unclear. Regions of this protein are also crucial for chemokine ligand binding, functional response of the receptor, and HIV co-receptor activity.^[21]

所有跟帖： 

• 你也太客气了.还理解不一样。 -soldanella- ♀ (241 bytes) () 11/27/2018 postreply 13:07:36

• 不过我认识的生物大牛也是非常反对贺这件事的 -soldanella- ♀ (0 bytes) () 11/27/2018 postreply 13:10:38

• 根据你引用的这段文字，那CCR5去掉后对防止乳腺癌也是有效的是好事了？ -linda2- ♀ (0 bytes) () 11/27/2018 postreply 13:14:01

• 是不是好事很难说。。。但她反过来了是肯定的。 -Morning3evening4- ♂ (0 bytes) () 11/27/2018 postreply 13:16:39

• 明白了，谢谢 -linda2- ♀ (0 bytes) () 11/27/2018 postreply 13:17:11

• 我看到的和你说的不一样.你的意思是变ccr5-Δ32反而防止癌症？赶紧申报 -soldanella- ♀ (0 bytes) () 11/27/2018 postreply 13:21:31

• 俺刚才专门查了几篇今年的研究论文，CCR5 抑制剂是治疗几种癌症的路子，他的引用貌似没有错。虽然不是直接ccr5-Δ32 -linda2- ♀ (0 bytes) () 11/27/2018 postreply 13:28:30

• 不是我的成果。我和你的讨论到此为止。 -Morning3evening4- ♂ (0 bytes) () 11/27/2018 postreply 13:32:04