molnupiravir, the oral pill, a game changer to pandemic?

来源: voiceofme 于 2021-10-02 11:16:56 [] [博客] [旧帖] [给我悄悄话] 阅读数 : (1906 bytes)
本帖于 2021-10-02 11:39:52 时间, 由普通用户 voiceofme 编辑

陌路僻壤菲亚： 7.3% of 385 patients who received the antiviral oral pills  were either hospitalized or died from Covid-19, compared with 14.1% of the 377 patients who received a placebo

Molnupiravir would be simpler for patients -- no IV required -- and it works differently, by changing the SARS-CoV-2 virus to inhibit replication.

https://www.cnn.com/2021/10/02/health/antiviral-pill-covid-19-explainer/index.html

In comparison, monoclonal antibody phase III trial result: the phase III outcomes trial in high-risk non-hospitalised patients with COVID-19 met its primary endpoint, showing the investigational antibody cocktail of casirivimab and imdevimab significantly reduced the risk of hospitalisation or death by 70% (1,200 mg intravenously [IV]) and 71% (2,400 mg IV) compared to placebo.

https://www.roche.com/media/releases/med-cor-2021-03-23.htm?

 

所有跟帖： 

• Not a game changer, but a money game. -heysofie- ♀ 给 heysofie 发送悄悄话 heysofie 的博客首页 (0 bytes) () 10/02/2021 postreply 11:54:00

• 这个会影响马药的销路 -oldmansea- ♂ 给 oldmansea 发送悄悄话 (0 bytes) () 10/03/2021 postreply 11:10:55

• 用药组0死亡还是很牛的，而且能口服成本也比抗体低多了 -小钉- ♂ 给 小钉 发送悄悄话 (0 bytes) () 10/02/2021 postreply 16:09:32

• 好像样本太小 -think_3- ♂ 给 think_3 发送悄悄话 (0 bytes) () 10/02/2021 postreply 17:29:06

• 测试被一独立监控机构叫停，因发现两组结果有明显差异，停后才知吃药的要好很多 -voiceofme- ♂ 给 voiceofme 发送悄悄话 voiceofme 的博客首页 (351 bytes) () 10/02/2021 postreply 17:37:37

• 多大样本？ -oldmansea- ♂ 给 oldmansea 发送悄悄话 (0 bytes) () 10/02/2021 postreply 19:18:44

• 总共760人，分两组，其中一组用安慰剂。 -think_3- ♂ 给 think_3 发送悄悄话 (0 bytes) () 10/02/2021 postreply 20:18:13

• 安慰剂组死了几个人？ -oldmansea- ♂ 给 oldmansea 发送悄悄话 (0 bytes) () 10/02/2021 postreply 20:20:10

• 8 ：0 -voiceofme- ♂ 给 voiceofme 发送悄悄话 voiceofme 的博客首页 (0 bytes) () 10/02/2021 postreply 20:49:04

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