sometimes, but if you always have a exit/hedge plan in place, you won't get killed even if you're terriblely wrong. Hope you're OK this time.
BTW, even though an approvable letter is expected to be the most likely outcome, as I previously predicted. I do think DNDN can go back to the $20s within the next 2 to 3 years. We'll know more as the company clarify the FDA data request next week or so. I don't see FDA hold this life-saving drug for another 4 to 5 years from desperate patients. If you have enough patience, you'll more than get your money back in time.
Happy trading.