最近的对新冠病毒的变异研究

来源: uptrend 于 2020-09-24 18:10:04 [档案] [博客] [旧帖] [给我悄悄话] 本文已被阅读：次 (2096 bytes)

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https://www.washingtonpost.com/health/2020/09/23/houston-coronavirus-mutations/?arc404=true

文章接近最后的两段:

这项研究发现了285个独立的突变位点，这些突变位点改变了刺突蛋白的物理结构单元，这是冠状病毒最重要的组成部分，因为它可以感染并伤害人类。在世界各地测序的其他基因组中，以前从未见过这些位点的四十九个变化。

该研究将某些峰值蛋白突变表征为“令人不安”。尽管该论文没有提供强有力的证据来证明刺突蛋白还会发生任何进一步的进化，但它表明这些重复的替代似乎显示，即随着该病毒与我们的身体和免疫系统相互作用，它可能正在学习新的方法来帮助它响应其宿主。

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The study found 285 separate mutation sites that change a physical building block of the spike protein, which is the most important part of the coronavirus in the sense that it is what allows it to infect and harm humans. Forty-nine of the changes at these sites had not been seen before in other genomes sequenced around the world.

The study characterizes some of the spike protein mutations as “disconcerting.” While the paper does not present strong proof that any additional evolution of the spike protein is occurring, it suggests that these repeated substitutions provide a hint that, as the virus interacts with our bodies and our immune systems, it may be learning new tricks that help it respond to its host.

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