She is running away from herself

You need to show more love toward her. Tightly hug her more. Spend more time together, doing fun things.

For some reason, she does not like herself that much and thinks very little of herself.

Give her some responsibility that she can handle with some effort on her part.  Be a role model by saying "I am responsible for this" or "It was my fault."

Give her some puzzle for her to think through, and then have her present her solution to you verbally while standing in front of you.

Stop focusing on her "problem" for now.