把房子租给照顾有缺陷病人的房客（做照顾病人的生意）有什么潜在的问题吗？

我有个房租想出租，有一个申请人说：

We have a business in which 4 clients live with us who are in treatment during the day for eating disorder/anxiety and depression

The clients will sleep there at the house but they go to class during the day and come back early evening Monday- Friday

其他方面还行。不知道这种房客回有什么潜在的问题？