The eternal puzzle of sciences is the following, in my opinion:

Nature, say, planet earth, is a result of long, complex, full evolution in itself. As we see it today, an equilibrium established by involving all cosmic factors. Therefore, it is way more sophisticated than any technological implements invented by men. In this sense, the sophistication of sciences/technology is so only to the human eye. In essence, human s/t is coarse and far from equilibrium, and therefore eventually serves to damage the well established nature. Only need to compare the making of a tree with the more complex men-made machine to see that.