【Serotonin 和 血糖 糖尿病】

Effects of serotonin on blood glucose and insulin levels of glucose- and streptozotocin-treated mice.

Sugimoto Y1, Kimura I, Yamada J, Watanabe Y, Takeuchi N, Horisaka K.

Author information

 

Abstract

Effects of serotonin (5-HT) on plasma glucose and serum insulin levels were studied in mice. In normal mice, 5-HT induced a dose-dependent hypoglycemia and an increase in serum insulin levels. 5-HT significantly inhibited glucose-induced hyperglycemia and increased glucose-stimulated insulin release. However, in streptozotocin-induced diabetic mice, 5-HT changed neither the glucose nor insulin levels. These results strongly suggest that 5-HT-induced hypoglycemia is brought on by increasing serum insulin levels.

PMID:

 

2148781

 

https://www.ncbi.nlm.nih.gov/pubmed/2148781