OK, 试试这个，

K=[ABn]/[A][B]

[ABn] = y

[A] = Cr - y, Cr: total RNA concentration

[B] = Cp - n * y, n: average # of proteins bound to each RNA, Cp = x

K = y/[(Cr - y)(x - n * y)].

x * Cr - (n * Cr + x)y + n * y * y = y/K

y**2 = y/(K * n) - x * Cr/n + (Cr + x/n)y

You have two parameters to fit. "n" is the number of average proteins bound to RNA.

换成线性参数，a=1/n, b=1/K

y**2 = a*b*y - a*x*Cr + (Cr + a*x) y

Hope this works ... 其他大拿们看到有什么错误的请指出／纠正。