其实,免疫功能低下的HIV病人感染新冠的案例中,病死率较高。 曾看过一篇论文

来源: 2021-01-23 19:18:16 [博客] [旧帖] [给我悄悄话] 本文已被阅读:

 

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(20)30305-2/fulltext

Results

17?282?905 adults were included, of whom 27?480 (0·16%) had HIV recorded. People living with HIV were more likely to be male, of Black ethnicity, and from a more deprived geographical area than the general population. 14?882 COVID-19 deaths occurred during the study period, with 25 among people with HIV. People living with HIV had higher risk of COVID-19 death than those without HIV after adjusting for age and sex: hazard ratio (HR) 2·90 (95% CI 1·96–4·30; p<0·0001). The association was attenuated, but risk remained high, after adjustment for deprivation, ethnicity, smoking and obesity: adjusted HR 2·59 (95% CI 1·74–3·84; p<0·0001). There was some evidence that the association was larger among people of Black ethnicity: HR 4·31 (95% CI 2·42–7·65) versus 1·84 (1·03–3·26) in non-Black individuals (p-interaction=0·044).

Interpretation

People with HIV in the UK seem to be at increased risk of COVID-19 mortality. Targeted policies should be considered to address this raised risk as the pandemic response evolves.
 
 
其实E博的设想不希奇,也许当年汪伪也是这么想的,避免正面对抗带来的国破家亡。
可是病毒感染对器官、组织、细胞的伤害,远不止于因子风暴。比如,对神经系统的直接损害,肺胞的不可逆性伤害,等等。
绥靖不能消除体内病毒,在缺乏有效药物时,自己的免疫是唯一有效的防御能力。医生们能做的,是尽可能控制免疫激活带来的附加伤害(collateral damages)